Journal of Research in Dental
and Maxillofacial Sciences
Volume 11, Issue 3 (9-2026)
J Res Dent Maxillofac Sci 2026, 11(3): 213-219 |
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Ethics code: IR.IAU.DENTAL.REC.1403.089
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Tehrani Z, Alamdari Mahd M, Nemati Anaraki S, Sanei E, Zahedirad S. Comparison of Discoloration of Primary Anterior Teeth Caused by Sideral Gocce versus Lipifer Liposomal Iron Drops: An In Vitro Study. J Res Dent Maxillofac Sci 2026; 11 (3) :213-219
URL: http://jrdms.dentaliau.ac.ir/article-1-1534-en.html
URL: http://jrdms.dentaliau.ac.ir/article-1-1534-en.html
1- Postgraduate Student, Department of Pediatric Dentistry, TeMS.C., Islamic Azad University, Tehran, Iran
2- Department of Pediatric Dentistry, TeMS.C., Islamic Azad University, Tehran, Iran
3- Dentist, Department of Restorative Dentistry, TeMS.c., Islamic Azad University, Tehran, Iran & Restorative Dentistry
4- Dentist, Department of Pediatric Dentistry, TeMS.c., Islamic Azad University, Tehran, Iran
5- Department of Pediatric Dentistry, TeMS.C., Islamic Azad University, Tehran, Iran ,zahedi@iautmu.ac.ir
2- Department of Pediatric Dentistry, TeMS.C., Islamic Azad University, Tehran, Iran
3- Dentist, Department of Restorative Dentistry, TeMS.c., Islamic Azad University, Tehran, Iran & Restorative Dentistry
4- Dentist, Department of Pediatric Dentistry, TeMS.c., Islamic Azad University, Tehran, Iran
5- Department of Pediatric Dentistry, TeMS.C., Islamic Azad University, Tehran, Iran ,
Abstract: (4 Views)
Background and Aim: Iron deficiency anemia (IDA) is a prevalent nutritional disorder among children. Oral iron supplements are essential for prevention and treatment of IDA but often cause tooth discoloration. Therefore, this study aimed to compare the color change (ΔE*) induced by Sideral® Gocce and Lipifer® iron drops in extracted primary anterior teeth over a 2-week exposure period.
Materials and Methods: In this in vitro study, 28 sound extracted human primary anterior teeth were randomly divided into two groups (n=14) of Sideral® Gocce (sucrosomial iron) and Lipifer® (nanoliposomal iron). Baseline color was measured with a VITA Easyshade® Compact spectrophotometer using the CIE L*a*b* system. Teeth underwent daily immersion in the respective iron drop, followed by rinsing and storage in artificial saliva. Color assessments were repeated after the first and second weeks. ΔE was calculated using the CIE76 formula for the following intervals: baseline to week 1 (ΔE*ab₁₋₀), week 1 to week 2 (ΔE*ab₂₋₁), and baseline to week 2 (ΔE*ab₂₋₀). Data were analyzed with an independent t-test (alpha=0.05).
Results: No significant differences were found between the groups for ΔE*ab₁₋₀ (P=0.095) or ΔE*ab₂₋₁ (P=0.122). However, Lipifer® caused significantly less cumulative discoloration of primary teeth than Sideral® Gocce over the 2-week exposure period (P=0.046).
Conclusion: The results showed that under the present in vitro conditions, Lipifer® caused significantly less cumulative discoloration of primary anterior teeth than Sideral® Gocce over the 2-week exposure period. No significant differences were observed between the groups during the shorter assessment intervals.
Materials and Methods: In this in vitro study, 28 sound extracted human primary anterior teeth were randomly divided into two groups (n=14) of Sideral® Gocce (sucrosomial iron) and Lipifer® (nanoliposomal iron). Baseline color was measured with a VITA Easyshade® Compact spectrophotometer using the CIE L*a*b* system. Teeth underwent daily immersion in the respective iron drop, followed by rinsing and storage in artificial saliva. Color assessments were repeated after the first and second weeks. ΔE was calculated using the CIE76 formula for the following intervals: baseline to week 1 (ΔE*ab₁₋₀), week 1 to week 2 (ΔE*ab₂₋₁), and baseline to week 2 (ΔE*ab₂₋₀). Data were analyzed with an independent t-test (alpha=0.05).
Results: No significant differences were found between the groups for ΔE*ab₁₋₀ (P=0.095) or ΔE*ab₂₋₁ (P=0.122). However, Lipifer® caused significantly less cumulative discoloration of primary teeth than Sideral® Gocce over the 2-week exposure period (P=0.046).
Conclusion: The results showed that under the present in vitro conditions, Lipifer® caused significantly less cumulative discoloration of primary anterior teeth than Sideral® Gocce over the 2-week exposure period. No significant differences were observed between the groups during the shorter assessment intervals.
Type of Study: Original article |
Subject:
pediatric
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