Journal of Research in Dental and Maxillofacial Sciences

en Comparison of Discoloration of Primary Anterior Teeth Caused by Sideral Gocce versus Lipifer Liposomal Iron Drops: An In Vitro Study pediatric pediatric Original article Original article <div style="text-align: justify;">Background and Aim: Iron deficiency anemia (IDA) is a prevalent nutritional disorder among children. Oral iron supplements are essential for prevention and treatment of IDA but often cause tooth discoloration. Therefore, this study aimed to compare the color change (ΔE*) induced by Sideral® Gocce and Lipifer® iron drops in extracted primary anterior teeth over a 2-week exposure period.    Materials and Methods: In this in vitro study, 28 sound extracted human primary anterior teeth were randomly divided into two groups (n=14) of Sideral® Gocce (sucrosomial iron) and Lipifer® (nanoliposomal iron). Baseline color was measured with a VITA Easyshade® Compact spectrophotometer using the CIE L*a*b* system. Teeth underwent daily immersion in the respective iron drop, followed by rinsing and storage in artificial saliva. Color assessments were repeated after the first and second weeks. ΔE was calculated using the CIE76 formula for the following intervals: baseline to week 1 (ΔE*ab₁₋₀), week 1 to week 2 (ΔE*ab₂₋₁), and baseline to week 2 (ΔE*ab₂₋₀). Data were analyzed with an independent t-test (alpha=0.05).    Results: No significant differences were found between the groups for ΔE*ab₁₋₀ (P=0.095) or ΔE*ab₂₋₁ (P=0.122). However, Lipifer® caused significantly less cumulative discoloration of primary teeth than Sideral® Gocce over the 2-week exposure period (P=0.046). Conclusion: The results showed that under the present in vitro conditions, Lipifer® caused significantly less cumulative discoloration of primary anterior teeth than Sideral® Gocce over the 2-week exposure period. No significant differences were observed between the groups during the shorter assessment intervals.  </div> Iron compounds, Iron deficiencies, Liposomes, Tooth, Deciduous, Tooth discoloration 213 219 http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-3311-1&slc_lang=en&sid=1 Zahra Tehrani 0386170487@iau.ir 100319475328460017618 100319475328460017618 No Postgraduate Student, Department of Pediatric Dentistry, TeMS.C., Islamic Azad University, Tehran, Iran Mandana Alamdari Mahd Mandanaalamdari@iau.ac.ir 100319475328460017619 100319475328460017619 No Department of Pediatric Dentistry, TeMS.C., Islamic Azad University, Tehran, Iran Saed Nemati Anaraki Sa.nemati@iau.ac.ir 100319475328460017620 100319475328460017620 No Dentist, Department of Restorative Dentistry, TeMS.c., Islamic Azad University, Tehran, Iran Elahe Sanei Elahesanei70@gmail.com 100319475328460017621 100319475328460017621 No Dentist, Department of Pediatric Dentistry, TeMS.c., Islamic Azad University, Tehran, Iran Sara Zahedirad zahedi@iautmu.ac.ir 100319475328460017622 100319475328460017622 Yes Department of Pediatric Dentistry, TeMS.C., Islamic Azad University, Tehran, Iran