Journal of Research in Dental
and Maxillofacial Sciences
Volume 10, Issue 4 (12-2025)
J Res Dent Maxillofac Sci 2025, 10(4): 285-291 |
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Aarasoor Cunniah L R, Nadarajan S, Narayanan V, Narayansamy D, Manjari C V S, Kolanji B. In Vitro Comparison of Morphological and Mechanical Properties, and Antimicrobial Efficacy of Silk Sutures Coated with Curcumin and Honey Extract. J Res Dent Maxillofac Sci 2025; 10 (4) :285-291
URL: http://jrdms.dentaliau.ac.ir/article-1-827-en.html
URL: http://jrdms.dentaliau.ac.ir/article-1-827-en.html
Lakshmi Rathan Aarasoor Cunniah *1 
, Suryakala Nadarajan2 , Vivek Narayanan2 , Damodharan Narayansamy3 , C V Swapna Manjari4 , Bakyalakshmi Kolanji5
, Suryakala Nadarajan2 , Vivek Narayanan2 , Damodharan Narayansamy3 , C V Swapna Manjari4 , Bakyalakshmi Kolanji5
1- Department of Oral and Maxillofacial Surgery, SRM Kattankulathur Dental College & Hospital, SRM Institute of Science and Technology, SRM Nagar, Potheri, Chengalpattu district, Tamil Nadu State, India , lakshmir5@srmist.edu.in
2- Department of Oral and Maxillofacial Surgery, SRM Kattankulathur Dental College & Hospital, SRM Institute of Science and Technology, SRM Nagar, Potheri, Chengalpattu district, Tamil Nadu State, India
3- Department of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, SRM Nagar, Potheri, Chengalpattu district, Tamil Nadu State, India
4- Department of Microbiology, SRM Medical College & Hospital, SRM Institute of Science and Technology, SRM Nagar, Potheri, Chengalpattu district, Tamil Nadu State, India
5- Department of Public Health Dentistry, Government Dental College & Hospital, Pudukottai
2- Department of Oral and Maxillofacial Surgery, SRM Kattankulathur Dental College & Hospital, SRM Institute of Science and Technology, SRM Nagar, Potheri, Chengalpattu district, Tamil Nadu State, India
3- Department of Pharmaceutics, SRM College of Pharmacy, SRM Institute of Science and Technology, SRM Nagar, Potheri, Chengalpattu district, Tamil Nadu State, India
4- Department of Microbiology, SRM Medical College & Hospital, SRM Institute of Science and Technology, SRM Nagar, Potheri, Chengalpattu district, Tamil Nadu State, India
5- Department of Public Health Dentistry, Government Dental College & Hospital, Pudukottai
Abstract: (14 Views)
Background and Aim: Surgical sutures are necessary to achieve hemostasis at the surgical site and promote healing. Currently, antibiotic-coated sutures are used to inhibit bacterial adhesion and proliferation. However, they can lead to bacterial resistance. To overcome this issue, herbal-coated suture materials are employed. This study aimed to assess the morphological and mechanical properties and antimicrobial efficacy of plain silk sutures with suture material coated with curcumin and honey.
Materials and Methods: This in vitro study included three groups (n=3). Group A consisted of plain silk sutures, group B consisted of silk sutures coated with curcumin, and group C consisted of silk sutures coated with honey extract. Morphological assessment was performed using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Tensile strength was measured using straight-pull and knot-pull tests on a tensile tester, and antimicrobial efficacy was evaluated using antimicrobial culture tests for the three groups. Statistical analysis was carried out using SPSS version 22.0.
Results: The morphology of coated sutures was validated by SEM images and EDS analysis. The tensile strength was not significantly different among the three groups, as assessed by the straight pull test (P=0.494) and knot pull test (P=0.707). Group A demonstrated no antibacterial activity. Group B demonstrated increased resistance to Pseudomonas aeruginosa (P. aeruginosa) (P=0.034), while Group C showed resistance to Escherichia coli (E. coli) (P=0.037).
Conclusion: The results showed that honey-coated sutures were highly resilient and had excellent antimicrobial properties. Curcumin-coated sutures expressed less resilience with better antimicrobial properties.
Materials and Methods: This in vitro study included three groups (n=3). Group A consisted of plain silk sutures, group B consisted of silk sutures coated with curcumin, and group C consisted of silk sutures coated with honey extract. Morphological assessment was performed using scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). Tensile strength was measured using straight-pull and knot-pull tests on a tensile tester, and antimicrobial efficacy was evaluated using antimicrobial culture tests for the three groups. Statistical analysis was carried out using SPSS version 22.0.
Results: The morphology of coated sutures was validated by SEM images and EDS analysis. The tensile strength was not significantly different among the three groups, as assessed by the straight pull test (P=0.494) and knot pull test (P=0.707). Group A demonstrated no antibacterial activity. Group B demonstrated increased resistance to Pseudomonas aeruginosa (P. aeruginosa) (P=0.034), while Group C showed resistance to Escherichia coli (E. coli) (P=0.037).
Conclusion: The results showed that honey-coated sutures were highly resilient and had excellent antimicrobial properties. Curcumin-coated sutures expressed less resilience with better antimicrobial properties.
Keywords: Anti-Infective Agents, Plant Extracts, Infection Control, Microscopy, Electron, Scanning, Wound Healing
Type of Study: Original article |
Subject:
Oral & maxillofacial surgery
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