Volume 8, Issue 4 (11-2023)                   J Res Dent Maxillofac Sci 2023, 8(4): 295-301 | Back to browse issues page


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Shoorgashti R, Etemadi A, Mirzaee S, Shoorgashti R. Correlation of Periodontitis and In Vitro Fertilization Outcome: A Literature Review. J Res Dent Maxillofac Sci 2023; 8 (4) :295-301
URL: http://jrdms.dentaliau.ac.ir/article-1-474-en.html
1- Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
2- Department of Periodontics, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. Laser Research Center of Dentistry, Tehran University of Medical Sciences, Tehran, Iran , a-etemadi@farabi.tums.ac.ir
3- Faculty of Nursing, Islamic Azad University, Neyshabur, Iran
Abstract:   (861 Views)
Background and Aim: This study reviewed the literature regarding the correlation of periodontal disease and outcome of in vitro fertilization (IVF).
Materials and Methods: "IVF", "In Vitro Fertilization", and "Periodontitis" were searched in PubMed, Web of Science, and Google Scholar databases
to find English articles published up to August 2022. A free online resource developed by the Canadian Agency for Drugs and Technologies in Health
was used to search the grey literature. Duplicate screening and extraction of citations were also carried out. No search filter was applied during
searching. Two independent reviewers evaluated the title and abstract of the retrieved articles. Next, the articles retrieved in the initial search
were reviewed independently for relevant information to the research question.

Results: The relationship between periodontitis and IVF has been studied in a limited number of studies. According to most articles, periodontal
disease may affect IVF implantation and vice versa in women who want to conceive through this procedure. Low sperm motility and reduction in
sperm count were also seen in males with periodontitis. Only one study found no correlation between the presence of periodontal disease and
unwanted IVF results.
   Conclusion: According to the results, periodontitis can impair the reproductive function since it causes systemic bacteremia. Oral health should
be addressed by the primary care providers before the onset of any fertility treatment. There is; however, a need for further investigations into the
possible implications of periodontal disease in women seeking fertility care
.  
Full-Text [PDF 627 kb]   (216 Downloads) |   |   Full-Text (HTML)  (125 Views)  
Type of Study: Review article | Subject: Periodontology

References
1. Nazir MA. Prevalence of periodontal disease, its association with systemic diseases and prevention. Int J Health Sci (Qassim). 2017 Apr-Jun;11(2):72-80.
2. Pavlatou A, Tsami A, Vlahos N, Mantzavinos T, Vrotsos I. The effect of in vitro fertilization on gingival inflammation according to women's periodontal status: clinical data. J Int Acad Perio-dontol. 2013 Apr;15(2):36-42.
3. Etemadi A, Hamidain M, Parker S, Chiniforush N. Blue Light Photodynamic Therapy With Curcumin and Riboflavin in the Management of Periodontitis: A Systematic Review. J Lasers Med Sci. 2021 Apr 21;12:e15. [DOI:10.34172/jlms.2021.15] [PMID] []
4. Tao DY, Zhu JL, Xie CY, Kuang YP, Chai WR, Lo ECM, Ye W, Li F, Feng XP, Lu HX. Relationship between periodontal disease and male infertility: A case-control study. Oral Dis. 2021 Apr;27(3):624-31. [DOI:10.1111/odi.13552] [PMID]
5. Kinane DF, Marshall GJ. Periodontal manifestations of system-ic disease. Aust Dent J. 2001 Mar;46(1):2-12. [DOI:10.1111/j.1834-7819.2001.tb00267.x] [PMID]
6. Tkacz K, Gill J, McLernon M. Necrotising periodontal diseases and alcohol misuse - a cause of osteonecrosis? Br Dent J. 2021 Aug;231(4):225-31. [DOI:10.1038/s41415-021-3272-9] [PMID] []
7. Bui FQ, Almeida-da-Silva CLC, Huynh B, Trinh A, Liu J, Wood-ward J, Asadi H, Ojcius DM. Association between periodontal pathogens and systemic disease. Biomed J. 2019 Feb;42(1):27-35. [DOI:10.1016/j.bj.2018.12.001] [PMID] []
8. Lecaplain B, Badran Z, Soueidan A, Prud'homme T, Gaudin A. Periodontitis, erectile dysfunction, reproductive hormones, and semen quality: A systematic review. Andrology. 2021 May;9(3):769-80. [DOI:10.1111/andr.12961] [PMID]
9. Muñoz Aguilera E, Suvan J, Buti J, Czesnikiewicz-Guzik M, Bar-bosa Ribeiro A, Orlandi M, Guzik TJ, Hingorani AD, Nart J, D'Aiuto F. Periodontitis is associated with hypertension: a sys-tematic review and meta-analysis. Cardiovasc Res. 2020 Jan 1;116(1):28-39. [DOI:10.1093/cvr/cvz201] [PMID]
10. Borsa L, Dubois M, Sacco G, Lupi L. Analysis the Link be-tween Periodontal Diseases and Alzheimer's Disease: A System-atic Review. Int J Environ Res Public Health. 2021 Sep 3;18(17):9312. [DOI:10.3390/ijerph18179312] [PMID] []
11. Moura-Grec PG, Marsicano JA, Carvalho CA, Sales-Peres SH. Obesity and periodontitis: systematic review and meta-analysis. Cien Saude Colet. 2014 Jun;19(6):1763-72. [DOI:10.1590/1413-81232014196.13482013] [PMID]
12. Klinger A, Hain B, Yaffe H, Schonberger O. Periodontal status of males attending an in vitro fertilization clinic. J Clin Periodon-tol. 2011 Jun;38(6):542-6. [DOI:10.1111/j.1600-051X.2011.01720.x] [PMID]
13. Carson SA, Kallen AN. Diagnosis and Management of Infertili-ty: A Review. JAMA. 2021 Jul 6;326(1):65-76. [DOI:10.1001/jama.2021.4788] [PMID] []
14. Machado V, Lopes J, Patrão M, Botelho J, Proença L, Mendes JJ. Validity of the association between periodontitis and female infertility conditions: a concise review. Reproduction. 2020 Sep;160(3):R41-R54. [DOI:10.1530/REP-20-0176] [PMID]
15. Yildiz Telatar G, Gürlek B, Telatar BC. Periodontal and caries status in unexplained female infertility: A case-control study. J Periodontol. 2021 Mar;92(3):446-54. [DOI:10.1002/JPER.20-0394] [PMID]
16. Chidambar CK, Shankar SM, Agarwal RK, Bhushan KS, Guru-raj SB. Evaluation of Periodontal Status among Men Undergoing Infertility Treatment. J Hum Reprod Sci. 2019 Apr-Jun;12(2):130-5. [DOI:10.4103/jhrs.JHRS_168_18] [PMID] []
17. Smadi L. Gingival and periodontal changes in patients under-going in vitro fertilization treatment: A clinical study. Indian J Dent Res. 2017 Nov-Dec;28(6):650-4. [DOI:10.4103/ijdr.IJDR_712_16] [PMID]
18. Khalife D, Khalil A, Itani MN, Khalifeh F, Faour S, Salame A, Ghazeeri G. No association between the presence of periodontal disease and poor IVF outcomes: a pilot study. Int J Womens Health. 2019 Jun 10;11:363-70. [DOI:10.2147/IJWH.S202135] [PMID] []
19. Rocca JP, Fornaini C, Wang Z, Tan L, Merigo E. Focal Infection and Periodontitis: A Narrative Report and New Possi-ble Approaches. Int J Microbiol. 2020 Oct 29; 2020: 8875612. [DOI:10.1155/2020/8875612] [PMID] []
20. Hart R, Doherty DA, Pennell CE, Newnham IA, Newnham JP. Periodontal disease: a potential modifiable risk factor limiting conception. Hum Reprod. 2012 May;27(5):1332-42. [DOI:10.1093/humrep/des034] [PMID]
21. Katz DJ, Teloken P, Shoshany O. Male infertility - The other side of the equation. Aust Fam Physician. 2017 Sep; 46(9):641-6.
22. Zhang L, Jiang F, Qi R, Fu W, Wang Y, Gui D. Pregnancy out-comes in patients with tubal infertility following laparoscopic treatment: a multivariate predictive study. Ann Palliat Med. 2021 Jan;10(1):462. [DOI:10.21037/apm-20-2347] [PMID]
23. Dong SQ, Zhao XL, Sun Y, Zhang JW. Comparative efficacy and safety of complementary and alternative therapies for tubal obstructive infertility: A protocol for network meta-analysis. Medicine (Baltimore). 2021 Feb 19;100(7):e 24810. [DOI:10.1097/MD.0000000000024810] [PMID] []
24. Fainberg J, Kashanian JA. Recent advances in understanding and managing male infertility. F1000 Res. 2019 May 16;8:F1000 Faculty Rev-670. [DOI:10.12688/f1000research.17076.1] [PMID] []
25. Sharma R, Agarwal A, Rohra VK, Assidi M, Abu-Elmagd M, Turki RF. Effects of increased paternal age on sperm quality, reproductive outcome and associated epigenetic risks to offspring. Reprod Biol Endocrinol. 2015 Apr 19;13: 35. [DOI:10.1186/s12958-015-0028-x] [PMID] []
26. Bieniek KW, Riedel HH. Bacterial foci in the teeth, oral cavi-ty, and jaw--secondary effects (remote action) of bacterial colonies with respect to bacteriospermia and subfertility in males. Andrologia. 1993 May-Jun;25(3):159-62. [DOI:10.1111/j.1439-0272.1993.tb02700.x] [PMID]
27. Khanna SS, Dhaimade PA, Malhotra S. Oral Health Status and Fertility Treatment Including IVF. J Obstet Gynaecol India. 2017 Dec;67(6):400-4. [DOI:10.1007/s13224-017-1025-0] [PMID] []
28. O'Neil TC. Plasma female sex-hormone levels and gingivitis in pregnancy. J Periodontol. 1979 Jun;50(6):279-82. [DOI:10.1902/jop.1979.50.6.279] [PMID]
29. Práger N, Pásztor N, Várnagy Á, Kozinszky Z, Baráth Z, Gorzó I, Radnai M. Idiopathic male infertility related to periodontal and caries status. J Clin Periodontol. 2017 Sep; 44(9):872-80. [DOI:10.1111/jcpe.12785] [PMID]
30. Varghese A, Balu P, R S, Muthu J, Vineela K. Salivary Interleukin-6 Levels among Polycystic Ovary Syndrome Patients with and Without Chronic Periodontitis - A Comparative Study. Contemp Clin Dent. 2019 Jul-Sep;10(3): 498-501. [DOI:10.4103/ccd.ccd_848_18] [PMID] []
31. Eggert-Kruse W, Neuer A, Clussmann C, Boit R, Geissler W, Rohr G, Strowitzki T. Seminal antibodies to human 60kd heat shock protein (HSP 60) in male partners of subfertile couples. Hum Reprod. 2002 Mar;17(3):726-35. [DOI:10.1093/humrep/17.3.726] [PMID]

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