Volume 6, Issue 3 (6-2021)                   J Res Dent Maxillofac Sci 2021, 6(3): 25-30 | Back to browse issues page

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Noori Nezhad A, Salem K, Zamanian M, Aghaei S. Comparison of Serum Vitamin D and Calcium Levels Between Children with Longer Than Normal Eruption Time of First Deciduous Tooth and Control Group. J Res Dent Maxillofac Sci 2021; 6 (3) :25-30
URL: http://jrdms.dentaliau.ac.ir/article-1-311-en.html
1- Private Practice, Tehran, Iran
2- Pediatric Dentistry Dept, Faculty of Dentistry,Tehran Medical Sciences,Islamic Azad University, Tehran, Iran.
3- Pediatric Dentistry Dept, Faculty of Dentistry,Tehran Medical Sciences, Islamic Azad University, Tehran, Iran , saba_aghaee@yahoo.com
Abstract:   (1341 Views)

Background and Aim: Tooth eruption is a multifaceted physiological process, which can be delayed by factors such as malnutrition. This study aimed to compare the serum levels of vitamin D and calcium in infants with a longer than normal eruption time of the first deciduous tooth with the control group (normal eruption).

Materials and Methods: In this case-control study, serum levels of vitamin D in 61 children with a mean age of normal dental eruption in Iranian children (8 months and less) were compared with 61 children with eruption age of more than 8 months. The children were matched in terms of age, sex, place of birth and residence, age of birth, birth weight, and other eruption-related items. Student's t-test, analysis of variance (ANOVA), and chi-square test were used for statistical analysis.

Results: The first erupted tooth in all infants was the mandibular incisor. The mean serum level of vitamin D was 38.1±24.1 ng/ml in infants with eruption age of 8 months or less and 40.0±21.5 ng/ml in the group of eruption age over 8 months (P=0.63). Serum calcium level was 10.03±0.55 mg/dl in the first group and 9.92±0.57 mg/dl in the second group (P=0.28). There was no significant relationship between gender, maternal education, A+D supplementation, infant nutrition (breast milk, formula, and combination), and different levels of vitamin D (deficient, inadequate, adequate, and toxic) with the average age of eruption of the first deciduous tooth (P>0.05).

Conclusion: It seems that serum vitamin D and calcium levels in this age group do not affect the eruption time of deciduous teeth.

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Type of Study: Original article | Subject: Oral medicine

1. Poureslami H, Asl Aminabadi N, Sighari Deljavan A, Erfanparast L, Sohrabi A, Jamali Z, et al. Does Timing of Eruption in First Primary Tooth Correlate with that of First Permanent Tooth? A 9-years Cohort Study. J Dent Res Dent Clin Dent Prospects. 2015;9(2):79-85. [DOI:10.15171/joddd.2015.0016]
2. Wu H, Chen T, Ma Q, Xu X, Xie K, Chen Y. Associations of maternal, perinatal and postnatal factors with the eruption timing of the first primary tooth. Sci Rep. 2019;9(1):2645. [DOI:10.1038/s41598-019-39572-w]
3. Soliman NL, El-Zainy MA, Hassan RM, Aly RM. Timing of deciduous teeth emergence in Egyptian children. East Mediterr Health J. 2011;17(11):875-81. [DOI:10.26719/2011.17.11.875]
4. Hughes TE, Bockmann MR, Seow K, Gotjamanos T, Gully N, Richards LC, et al. Strong Genetic Control of Emergence of Human Primary Incisors. J Dent Res. 2007;86(12):1160-5. [DOI:10.1177/154405910708601204]
5. Naik P, Faridi MMA, Batra P, Madhu SV. Oral Supplementation of Parturient Mothers with Vitamin D and Its Effect on 25OHD Status of Exclusively Breastfed Infants at 6 Months of Age: A Double-Blind Randomized Placebo Controlled Trial. Breastfeed Med. 2017;12(10):621-8. [DOI:10.1089/bfm.2016.0164]
6. Maghbooli Z, Hossein-Nezhad A, Shafaei AR, Karimi F, Madani FS, Larijani B. Vitamin D status in mothers and their newborns in Iran. BMC Pregnancy Childbirth. 2007;7:1. [DOI:10.1186/1471-2393-7-1]
7. Trivedi M, Faridi MMA, Aggarwal A, Madhu SV, Malhotra RK. Oral Vitamin D Supplementation to Mothers During Lactation-Effect of 25(OH)D Concentration on Exclusively Breastfed Infants at 6 Months of Age: A Randomized Double-Blind Placebo-Controlled Trial. Breastfeed Med. 2020 Apr;15(4):237-245. [DOI:10.1089/bfm.2019.0102]
8. Holman DJ, Yamaguchi K. Longitudinal analysis of deciduous tooth emergence: IV. Covariate effects in Japanese children. Am J Phys Anthropol. 2005;126(3):352-8. [DOI:10.1002/ajpa.10420]
9. Emdadi R, Chaichian S, Mahboubi M, Moradi Y, Akhlaghdoust M, Basharkhah A. Prevalence of Vitamin D Deficiency Among Women of Reproductive Age: A Multi Centric Study in Tehran. Shiraz E-Med J. 2016;17(11):e40745. [DOI:10.17795/semj40745]
10. Pettifor JM. Nutritional rickets: deficiency of vitamin D, calcium, or both? Am J Clin Nutr. 2004;80(6):1725S-9S. [DOI:10.1093/ajcn/80.6.1725S]
11. Saggese G, Vierucci F, Prodam F, Cardinale F, Cetin I, Chiappini E, et al. Vitamin D in pediatric age: consensus of the Italian Pediatric Society and the Italian Society of Preventive and Social Pediatrics, jointly with the Italian Federation of Pediatricians. Italian J Pediatr. 2018;44(1):51. [DOI:10.1186/s13052-018-0488-7]
12. Högler W. Complications of vitamin D deficiency from the foetus to the infant: One cause, one prevention, but who's responsibility? Best Pract Res Clin Endocrinol Metab. 2015;29(3):385-98. [DOI:10.1016/j.beem.2015.03.003]
13. Heaney RP, Davies KM, Chen TC, Holick MF, Barger-Lux MJ. Human serum 25-hydroxycholecalciferol response to extended oral dosing with cholecalciferol. Am J Clin Nutr. 2003 Jan;77(1):204-10. [DOI:10.1093/ajcn/77.1.204]
14. Jairam L, Konde S, Raj N, Kumar N. Vitamin D deficiency as an etiological factor in delayed eruption of primary teeth: A cross-sectional study. J Indian Soc Pedod Prev Dent. 2020;38(3):211-5.
15. Babaniamansour S, Hematyar M, Babaniamansour P, Babaniamansour A, Aliniagerdroudbari E. The Prevalence of Vitamin D Deficiency Among One to Six Year Old Children of Tehran, Iran. J Kermanshah Univ Med Sci. 2019;23(4):e95185. [DOI:10.5812/jkums.95185]
16. Mahmoodian J, Ghandehari M, Khojani M. Longitudinal study of time and sequence of primary teeth eruption in children, residents in Tehran, from birth (2000-2002). J Islam Dent Assoc IRAN (JIDA). 2005;17(1):34-9.
17. Speidel TD, Stearns G. The relation of vitamin D intake to the age of the infant at the time of eruption of the first deciduous incisor. J Pediatr. 1940;17(4):506-11. [DOI:10.1016/S0022-3476(40)80104-2]
18. Kim IJ, Lee HS, Ju HJ, Na JY, Oh HW. A cross-sectional study on the association between vitamin D levels and caries in the permanent dentition of Korean children. BMC Oral Health. 2018;18(1):43. [DOI:10.1186/s12903-018-0505-7]
19. Jartti T, Liimatainen U, Xepapadaki P, Vahlberg T, Bachert C, Finotto S, et al. Clinical correlates of rhinovirus infection in preschool asthma. Allergy. 2021 Jan;76(1):247-254. [DOI:10.1111/all.14479]
20. Suri L, Gagari E, Vastardis H. Delayed tooth eruption: pathogenesis, diagnosis, and treatment. A literature review. Am J Orthod Dentofacial Orthop. 2004;126(4):432-45. [DOI:10.1016/j.ajodo.2003.10.031]
21. Kaabneh MAF, Salama G, Sunna N. Impact of Oral Vitamin D Supplementation on First Tooth Eruption of Jordanian Premature Infants. J Royal Med Serv. 2016;23:11-9. [DOI:10.12816/0027100]
22. Dhamo B, Miliku K, Voortman T, Tiemeier H, Jaddoe VW, Wolvius EB, et al. The Associations of Maternal and Neonatal Vitamin D with Dental Development in Childhood. Curr Dev Nutr. 2019 Mar 7;3(4):nzy100. [DOI:10.1093/cdn/nzy100]
23. Delgado H, Habicht JP, Yarbrough C, Lechtig A, Martorell R, Malina RM, et al. Nutritional status and the timing of deciduous tooth eruption. Am J Clin Nutr. 1975;28(3):216-24. [DOI:10.1093/ajcn/28.3.216]

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