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:: Volume 6, Issue 1 (Journal of Research in Dental & Maxillofacial Sciences Winter 2021) ::
J Res Dentomaxillofac Sci 2021, 6(1): 19-23 Back to browse issues page
Evaluation of Dysplasia in Oral Lichen Planus Patients of Oral Medicine Department of Semnan University of Medical Sciences from 2013 to 2018
M Jalili Sadrabad1 , Y Sahraeeyan2 , F Sohrabpoor2 , M Mirmohammadkhani3 , SH Sohanian * 4
1- Assistant Professor, Oral Medicine Dept, Dental School, Semnan University of Medical Sciences, Semnan, Iran.
2- Dental Student, Student Research Committee, Dental School, Semnan University of Medical Sciences, Semnan, Iran.
3- Social Determinants of Health Research Center, Department of Epidemiology & Statistics, Faculty of Medicine, Semnan University of Medical Sciences, Semnan, Iran.
4- Assistant Professor, Oral and Maxillofacial Pathology Dept, Dental School, Semnan University of Medical Sciences, Semnan, Iran. , dr.sh.sohanian@gmail.com
Abstract:   (134 Views)
Background and Aim: Oral lichen planus (OLP) is a chronic mucocutaneous disease, which is considered a precancerous condition. OLP is a multifactorial disease with no conclusive treatment. Timely diagnosis and treatment of oral lesions are necessary steps to prevent malignant transformations and severe complications of oral cancer. This study aimed to evaluate the frequency and severity of malignant transformations in OLP.
Materials and Methods: In this study, 2400 files of patients who presented to the Oral Medicine Department of the Dental School of Semnan University of Medical Sciences from 2013 to 2018 were evaluated. Data were statistically analyzed using SPSS.
Results: Forty patients (9 males and 31 females with the mean age of 45.2 years) were diagnosed with OLP (1.6%). The most common type of OLP was reticular (75%), and the least common was the ulcerative type. Since toluidine blue staining was positive for 4 patients (10%), a biopsy was done. The histopathological examinations showed one case with dysplasia (2.5%) and one case of carcinoma (2.5%).
Conclusion: According to the results, carcinoma and dysplasia can develop in OLP patients. Regular follow-ups are strongly recommended for timely diagnosis and treatment of malignant transformations.
Keywords: Lichen Planus, Oral, Squamous Cell Carcinoma, Mouth Neoplasms
Full-Text [PDF 232 kb]   (41 Downloads) |   |   Full-Text (HTML)  (34 Views)  
Type of Study: Original article | Subject: Oral medicine
* Corresponding Author Address: Semnan University of Medical Sciences
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Jalili Sadrabad M, Sahraeeyan Y, Sohrabpoor F, Mirmohammadkhani M, Sohanian S. Evaluation of Dysplasia in Oral Lichen Planus Patients of Oral Medicine Department of Semnan University of Medical Sciences from 2013 to 2018. J Res Dentomaxillofac Sci. 2021; 6 (1) :19-23
URL: http://jrdms.dentaliau.ac.ir/article-1-296-en.html


Volume 6, Issue 1 (Journal of Research in Dental & Maxillofacial Sciences Winter 2021) Back to browse issues page
Journal of Research in Dental and Maxillofacial Sciences
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