Volume 10, Issue 2 (6-2025)
J Res Dent Maxillofac Sci 2025, 10(2): 152-158 |
Back to browse issues page
Ethics code: IR.TUMS.DENTISTRY.REC.1398.122
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Motevaselian F, Mohaghegh B, Sadeghi F, Rafeie N, Abbasi M, ranjbar omrani L. Dentin Remineralizing Potential of a Bioactive Composite Resin Versus a Conventional Composite Resin: Mineral Index and Microhardness Analysis. J Res Dent Maxillofac Sci 2025; 10 (2) :152-158
URL: http://jrdms.dentaliau.ac.ir/article-1-764-en.html
URL: http://jrdms.dentaliau.ac.ir/article-1-764-en.html
Fariba Motevaselian1 
, Behnam Mohaghegh2 , Farzaneh Sadeghi1 , Niyousha Rafeie3 , Mehdi Abbasi *4 , Ladan Ranjbar omrani5
, Behnam Mohaghegh2 , Farzaneh Sadeghi1 , Niyousha Rafeie3 , Mehdi Abbasi *4 , Ladan Ranjbar omrani5
1- Restorative Department, Dental School, Tehran University of Medical Sciences, Tehran, Iran.
2- Dentist, Private practice, Tehran, Iran.
3- Dental Research Center, Dentistry Research Institute, Dental School, Tehran University of Medical Science, Tehran, Iran.
4- Restorative Department, Dental School, Tehran University of Medical Sciences, Tehran, Iran. ,Abbasimahdi84@gmail.com
5- RRestorative Department, Dental School, Tehran University of Medical Sciences, Tehran, Iran.
2- Dentist, Private practice, Tehran, Iran.
3- Dental Research Center, Dentistry Research Institute, Dental School, Tehran University of Medical Science, Tehran, Iran.
4- Restorative Department, Dental School, Tehran University of Medical Sciences, Tehran, Iran. ,
5- RRestorative Department, Dental School, Tehran University of Medical Sciences, Tehran, Iran.
Abstract: (78 Views)
Background and Aim: This study aimed to compare the dentin demineralization inhibitory potential of a bioactive composite resin (ACTIVA-BioActive) with a conventional composite resin.
Materials and Methods: In this in vitro experimental study, 45 class V cavities were prepared on the root surface of extracted human third molars. The teeth were then immersed in a demineralizing solution (lactic acid, pH=4.5) at 37˚C for 3 days to induce the formation of secondary caries. The cavities were restored with Single bond 2 + Z250 (group A), ACTIVA BioActive (group B), and Single bond 2 + ACTIVA BioActive (group C). The dentin microhardness was measured close to the restoration margin (marginally exposed dentin), and at approximately 4 mm distance from the margin in a varnish-covered dentin area (protected dentin). Three measurements were made at each site at 50, 100, and 150 µm depths from the external dentin surface. Data were analyzed with one-way ANOVA and Tukey test (alpha=0.05).
Results: The highest Vickers hardness number (VHN) was observed in ACTIVA+ bonding agent (49.46±4.15), followed by Z250 (44.57±3.87), and ACTIVA (43.44±3.76) group. The mineral index was significantly higher in ACTIVA+ bonding agent (76.87±3.80) compared to other groups while no significant difference was observed between ACTIVA (70.85±4.06) and Z250 (71.98±3.09) in this regard (P<0.001).
Conclusion: The results showed that flowable ACTIVA BioActive composite used with Single bond 2 resulted in a significantly smaller reduction in dentin microhardness and reduced secondary caries formation. ACTIVA BioActive with no adhesive had no advantage over Z250 composite.
Materials and Methods: In this in vitro experimental study, 45 class V cavities were prepared on the root surface of extracted human third molars. The teeth were then immersed in a demineralizing solution (lactic acid, pH=4.5) at 37˚C for 3 days to induce the formation of secondary caries. The cavities were restored with Single bond 2 + Z250 (group A), ACTIVA BioActive (group B), and Single bond 2 + ACTIVA BioActive (group C). The dentin microhardness was measured close to the restoration margin (marginally exposed dentin), and at approximately 4 mm distance from the margin in a varnish-covered dentin area (protected dentin). Three measurements were made at each site at 50, 100, and 150 µm depths from the external dentin surface. Data were analyzed with one-way ANOVA and Tukey test (alpha=0.05).
Results: The highest Vickers hardness number (VHN) was observed in ACTIVA+ bonding agent (49.46±4.15), followed by Z250 (44.57±3.87), and ACTIVA (43.44±3.76) group. The mineral index was significantly higher in ACTIVA+ bonding agent (76.87±3.80) compared to other groups while no significant difference was observed between ACTIVA (70.85±4.06) and Z250 (71.98±3.09) in this regard (P<0.001).
Conclusion: The results showed that flowable ACTIVA BioActive composite used with Single bond 2 resulted in a significantly smaller reduction in dentin microhardness and reduced secondary caries formation. ACTIVA BioActive with no adhesive had no advantage over Z250 composite.
Keywords: Activa Bioactive Base Liner, Activa Bioactive Restorative, Flowable Hybrid Composite, Tooth Remineralization
Type of Study: Original article |
Subject:
Restorative Dentistry
References
1. Craig RG, Powers JM. Craig's Restorative Dental Materials. 14th ed. St. Louis: Mosby; 2018. Chapter 1, Biological considerations; p. 1-15.
2. Cheng L, Zhang K, Zhang N, Melo MAS, Weir MD, Zhou XD, Bai YX, Reynolds MA, Xu HHK. Developing a New Generation of Antimicrobial and Bioactive Dental Resins. J Dent Res. 2017 Jul;96(8):855-63. [DOI:10.1177/0022034517709739] [PMID] []
3. Savarino L, Breschi L, Tedaldi M, Ciapetti G, Tarabusi C, Greco M, Giunti A, Prati C. Ability of restorative and fluoride releasing materials to prevent marginal dentine demineralization. Biomaterials. 2004 Mar;25(6):1011-7. [DOI:10.1016/S0142-9612(03)00628-8] [PMID]
4. Brunthaler A, König F, Lucas T, Sperr W, Schedle A. Longevity of direct resin composite restorations in posterior teeth. Clin Oral Investig. 2003 Jun;7(2):63-70. [DOI:10.1007/s00784-003-0206-7] [PMID]
5. Opdam NJ, Loomans BA, Roeters FJ, Bronkhorst EM. Five-year clinical performance of posterior resin composite restorations placed by dental students. J Dent. 2004 Jul;32(5):379-83. [DOI:10.1016/j.jdent.2004.02.005] [PMID]
6. M R, Sajjan GS, B N K, Mittal N. Effect of different placement techniques on marginal microleakage of deep class-II cavities restored with two composite resin formulations. J Conserv Dent. 2010 Jan;13(1):9-15. [DOI:10.4103/0972-0707.62633] [PMID] []
7. Chatzistavrou X, Lefkelidou A, Papadopoulou L, Pavlidou E, Paraskevopoulos KM, Fenno JC, Flannagan S, González-Cabezas C, Kotsanos N, Papagerakis P. Bactericidal and Bioactive Dental Composites. Front Physiol. 2018 Feb 16;9:103. [DOI:10.3389/fphys.2018.00103] [PMID] []
8. Chatzistavrou X, Fenno JC, Faulk D, Badylak S, Kasuga T, Boccaccini AR, et al. Fabrication and characterization of bioactive and antibacterial composites for dental applications. Acta Biomater. 2014 Aug;10(8):3723-32. [DOI:10.1016/j.actbio.2014.04.030] [PMID]
9. Alkhudhairy FI, Ahmad ZH. Comparison of Shear Bond Strength and Microleakage of Various Bulk-fill Bioactive Dentin substitutes: An in vitro Study. J Contemp Dent Pract. 2016 Dec 1;17(12):997-1002. [DOI:10.5005/jp-journals-10024-1970] [PMID]
10. Croll TP, Berg JH, Donly KJ. Dental repair material: a resin-modified glass-ionomer bioactive ionic resin-based composite. Compend Contin Educ Dent. 2015 Jan;36(1):60-5.
11. Porenczuk A, Jankiewicz B, Naurecka M, Bartosewicz B, Sierakowski B, Gozdowski D, et al. A comparison of the remineralizing potential of dental restorative materials by analyzing their fluoride release profiles. Adv Clin Exp Med. 2019 Jun;28(6):815-23. [DOI:10.17219/acem/94140] [PMID]
12. Zmener O, Pameijer CH, Hernández S. Resistance against bacterial leakage of four luting agents used for cementation of complete cast crowns. Am J Dent. 2014 Feb;27(1):51-5.
13. Khamverdi Z, Kordestani M, Soltanian AR. Effect of Proanthocyanidin, Fluoride and Casein Phosphopeptide Amorphous Calcium Phosphate Remineralizing Agents on Microhardness of Demineralized Dentin. J Dent (Tehran). 2017 Mar;14(2):76-83.
14. Elsayed HE, Hammouda HE. Comparative Evaluation of Microleakage of Different Class V Cavity Preparation Restored with Composite in Primary Molars: An In Vitro Study. Mansoura Journal of Dentistry. 2023;10(1):48-52. [DOI:10.21608/mjd.2023.288116]
15. Gale MS, Darvell BW. Thermal cycling procedures for laboratory testing of dental restorations. J Dent. 1999 Feb;27(2):89-99. [DOI:10.1016/S0300-5712(98)00037-2] [PMID]
16. Franc J, Moravec P, Dědič V, Roy U, Elhadidy H, Minárik P, et al. Microhardness study of Cd1-x ZnxTe1-ySey crystals for X-ray and gamma ray detectors. Materials Today Communications. 2020 Sep 1;24:101014. [DOI:10.1016/j.mtcomm.2020.101014]
17. Moreira FD, Kleinberg MN, Arruda HF, Freitas FN, Parente MM, De Albuquerque VH, et al. A novel Vickers hardness measurement technique based on Adaptive Balloon Active Contour Method. Expert systems with applications. 2016 Mar 1;45:294-306. [DOI:10.1016/j.eswa.2015.09.025]
18. Imbery TA, Namboodiri A, Duncan A, Amos R, Best AM, Moon PC. Evaluating dentin surface treatments for resin-modified glass ionomer restorative materials. Oper Dent. 2013 Jul-Aug;38(4):429-38. [DOI:10.2341/12-162-L] [PMID]
19. Yamamoto K, Kojima H, Tsutsumi T, Oguchi H. Effects of tooth-conditioning agents on bond strength of a resin-modified glass-ionomer sealant to enamel. J Dent. 2003 Jan;31(1):13-8. [DOI:10.1016/S0300-5712(02)00086-6] [PMID]
20. Poggio C, Beltrami R, Scribante A, Colombo M, Lombardini M. Effects of dentin surface treatments on shear bond strength of glass-ionomer cements. Ann Stomatol (Roma). 2014 Mar 31;5(1):15-22. [DOI:10.11138/ads/2014.5.1.015]
21. Imbery TA, Namboodiri A, Duncan A, Amos R, Best AM, Moon PC. Evaluating dentin surface treatments for resin-modified glass ionomer restorative materials. Oper Dent. 2013 Jul-Aug;38(4):429-38. [DOI:10.2341/12-162-L] [PMID]
22. Valanezhad A, Odatsu T, Udoh K, Shiraishi T, Sawase T, Watanabe I. Modification of resin modified glass ionomer cement by addition of bioactive glass nanoparticles. J Mater Sci Mater Med. 2016 Jan;27(1):3. [DOI:10.1007/s10856-015-5614-0] [PMID]
23. Kasraei S, Haghi S, Farzad A, Malek M, Nejadkarimi S. Comparative of flexural strength, hardness, and fluoride release of two bioactive restorative materials with RMGI and composite resin. Brazilian Journal of Oral Sciences. 2022 May 9;21:e225263. [DOI:10.20396/bjos.v21i00.8665263]
24. Garcia IM, Balhaddad AA, Aljuboori N, Ibrahim MS, Mokeem L, Ogubunka A, Collares FM, de Melo MAS. Wear Behavior and Surface Quality of Dental Bioactive Ions-Releasing Resins Under Simulated Chewing Conditions. Front Oral Health. 2021 Feb 12;2:628026. [DOI:10.3389/froh.2021.628026] [PMID] []
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
