Volume 6, Issue 2 (Journal of Research in Dental & Maxillofacial Sciences Spring 2021)                   J Res Dent Maxillofac Sci 2021, 6(2): 29-35 | Back to browse issues page

XML Print

Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Ebrahimi H, Sharifzadeh S, Meftahpour H. Role of Photodynamic Therapy in the Treatment of Oral Cancer: A Review. J Res Dent Maxillofac Sci. 2021; 6 (2) :29-35
URL: http://jrdms.dentaliau.ac.ir/article-1-307-en.html
1- Oral Medicine Dept, Faculty of Dentistry, Tehran Medical Science, Islamic Azad University, Tehran, Iran
2- Oral Medicine Dept, Membership of Dental Material Research Center, Faculty of Dentistry, Tehran Medical Science, Islamic Azad University, Tehran, Iran , haniye.meftahpour@gmail.com
Abstract:   (1171 Views)
Oral cancer is a major public health problem worldwide and is among the ten most common cancers. Despite the advances in research and treatment, oral cancer is still one of the major challenges in medical science. Common treatments for this cancer include surgery, radiotherapy, and chemotherapy, as well as adjuvant photodynamic therapy (PDT). The aim of this study was to evaluate oral cancer and its treatment methods with an emphasis on the use of adjuvant PDT. The present study is a review performed by searching the articles published in the past 20 years (2000-2020) in Elsevier, PubMed, Springer, and Wiley databases with “oral cancer”, “photodynamic therapy”, and “treatment modalities” keywords. Research shows that PDT can be an effective way to treat oral cancer due to its few side effects and minimal invasion. However, accurate evaluation of the efficacy of PDT requires further studies.
Full-Text [PDF 372 kb]   (645 Downloads) |   |   Full-Text (HTML)  (399 Views)  
Type of Study: Review article | Subject: Oral medicine

1. Pavani N, Srinivas P, Kothia N, Chandu V. Recent Advances in the Early Diagnosis of Oral Cancer: A Systematic Review. Int J Med Rev. 2017;4(4):119-25. [DOI:10.29252/IJMR-040406]
2. Rivera C. Essentials of oral cancer. Int J Clin Exp Pathol. 2015 Sep 1;8(9):11884-94.
3. Kumar M, Nanavati R, Modi TG, Dobariya C. Oral cancer: Etiology and risk factors: A review. J Cancer Res Ther. 2016 Apr-Jun;12(2):458-63. [DOI:10.4103/0973-1482.186696] [PMID]
4. Furness S, Glenny AM, Worthington HV, Pavitt S, Oliver R, Clarkson JE, Macluskey M, Chan KK, Conway DI; CSROC Expert Panel. Interventions for the treatment of oral cavity and oropharyngeal cancer: chemotherapy. Cochrane Database Syst Rev. 2010 Sep 8;(9):CD006386. [DOI:10.1002/14651858.CD006386.pub2]
5. Nitish Grag K, Singhal K. Potentially Oral Malignant Lesion and Oral Cancer and Future Diagnostic Techniques: A Review. Indian J Appl Res. 2013;3(6):421-5. [DOI:10.15373/2249555X/JUNE2013/141]
6. Prince VM, Papagerakis S, Prince ME. Oral Cancer and Cancer Stem Cells: Relevance to Oral Cancer Risk Factors, Premalignant Lesions, and Treatment. Curr Oral Health Rep. 2016;3:65-73. [DOI:10.1007/s40496-016-0081-3]
7. Dolmans DE, Fukumura D, Jain RK. Photodynamic therapy for cancer. Nat Rev Cancer. 2003 May;3(5):380-7. [DOI:10.1038/nrc1071] [PMID]
8. Jerjes W, Upile T, Akram S, Hopper C. The surgical palliation of advanced head and neck cancer using photodynamic therapy. Clin Oncol (R Coll Radiol). 2010 Nov;22(9):785-91. [DOI:10.1016/j.clon.2010.07.001] [PMID]
9. Rigual NR, Thankappan K, Cooper M, Sullivan MA, Dougherty T, Popat SR, Loree TR, Biel MA, Henderson B. Photodynamic therapy for head and neck dysplasia and cancer. Arch Otolaryngol Head Neck Surg. 2009 Aug;135(8):784-8. [DOI:10.1001/archoto.2009.98] [PMID] [PMCID]
10. Lorenz KJ, Maier H. Photodynamic therapy with metatetrahydroxyphenylchlorin (Foscan) in the management of squamous cell carcinoma of the head and neck: experience with 35 patients. Eur Arch Otorhinolaryngol. 2009;266:1937-44. [DOI:10.1007/s00405-009-0947-2] [PMID]
11. Biel MA. Photodynamic therapy of head and neck cancers. Methods Mol Biol. 2010;635:281-93. [DOI:10.1007/978-1-60761-697-9_18] [PMID]
12. Copper MP, Triesscheijn M, Tan IB, Ruevekamp MC, Stewart FA. Photodynamic therapy in the treatment of multiple primary tumours in the head and neck, located to the oral cavity and oropharynx. Clin Otolaryngol. 2007 Jun;32(3):185-9. [DOI:10.1111/j.1365-2273.2007.01441.x] [PMID]
13. Biel M. Advances in photodynamic therapy for the treatment of head and neck cancers. Lasers Surg Med. 2006 Jun;38(5):349-55. [DOI:10.1002/lsm.20368] [PMID]
14. Baom NM, Abdul Hamid G. Epidemiology of oral and pharyngeal cancer. Eur J Pharm Med Res. 2017;4(9):155-64.
15. Bhide SA, Nutting CM. Advances in radiotherapy for head and neck cancer. Oral Oncol. 2010 Jun;46(6):439-41. [DOI:10.1016/j.oraloncology.2010.03.005] [PMID]
16. Wong T, Wiesenfeld D. Oral Cancer. Aust Dent J. 2018 Mar;63 Suppl 1:S91-S99. [DOI:10.1111/adj.12594] [PMID]
17. Deng H, Sambrook PJ, Logan RM. The treatment of oral cancer: an overview for dental professionals. Aust Dent J. 2011 Sep;56(3):244-52, 341. [DOI:10.1111/j.1834-7819.2011.01349.x] [PMID]
18. Prelec, J, Laronde D. Treatment modalities of oral cancer. Can J Dent Hyg. 2014;48(1): 13-9.
19. Saini R, Lee NV, Liu KY, Poh CF. Prospects in the Application of Photodynamic Therapy in Oral Cancer and Premalignant Lesions. Cancers (Basel). 2016 Sep 2;8(9):83. [DOI:10.3390/cancers8090083] [PMID] [PMCID]
20. Andreadis D, Pavlou A-M, Sotiriou E, Vrani F, Ioannides D, Kolokotronis A. Utility of photodynamic therapy for the management of oral potentially malignant disorders and oral cancer. Translational Research in Oral Oncology. 2016;1:1-19. [DOI:10.1177/2057178X16669161]
21. Al-Delayme RMA, Radhi H, Farag A, Al-Allaq T, Virdee P, Almudamgha R, et al. Photodynamic Therapy as a Treatment Option for Oral Cancer and Dysplasia. Ann Med Health Sci Res. 2018;8:59-64.
22. Baskaran R, Lee J, Yang SG. Clinical development of photodynamic agents and therapeutic applications. Biomater Res. 2018 Sep 26;22:25. [DOI:10.1186/s40824-018-0140-z] [PMID] [PMCID]
23. Kubler AC. Photodynamic therapy. Med Laser Appl. 2005;20:37-45 [DOI:10.1016/j.mla.2005.02.001]
24. Mostafa D, Tarakji B. Photodynamic therapy in treatment of oral lichen planus. J Clin Med Res. 2015 Jun;7(6):393-9.. [DOI:10.14740/jocmr2147w] [PMID] [PMCID]
25. Durbec M, Cosmidis A, Fuchsmann C, Ramade A, Céruse P. Efficacy and safety of photodynamic therapy with temoporfin in curative treatment of recurrent carcinoma of the oral cavity and oropharynx. Eur Arch Otorhinolaryngol. 2013 Mar;270(4):1433-9. [DOI:10.1007/s00405-012-2083-7] [PMID]
26. Ikeda H, Tobita T, Ohba S, Uehara M, Asahina I. Treatment outcome of Photofrin-based photodynamic therapy for T1 and T2 oral squamous cell carcinoma and dysplasia. Photodiagnosis Photodyn Ther. 2013 Sep;10(3):229-35. [DOI:10.1016/j.pdpdt.2013.01.006] [PMID]
27. Jerjes W, Upile T, Hamdoon Z, Alexander Mosse C, Morcos M, Hopper C. Photodynamic therapy outcome for T1/T2 N0 oral squamous cell carcinoma. Lasers Surg Med. 2011 Aug;43(6):463-9. [DOI:10.1002/lsm.21071] [PMID]
28. Tan IB, Dolivet G, Ceruse P, Vander Poorten V, Roest G, Rauschning W. Temoporfin-mediated photodynamic therapy in patients with advanced, incurable head and neck cancer: A multicenter study. Head Neck. 2010 Dec;32(12):1597-604. [DOI:10.1002/hed.21368] [PMID]
29. Kübler AC, de Carpentier J, Hopper C, Leonard AG, Putnam G. Treatment of squamous cell carcinoma of the lip using Foscan-mediated photodynamic therapy. Int J Oral Maxillofac Surg. 2001 Dec;30(6):504-9. [DOI:10.1054/ijom.2001.0160] [PMID]
30. Hopper C, Kübler A, Lewis H, Tan IB, Putnam G. mTHPC-mediated photodynamic therapy for early oral squamous cell carcinoma. Int J Cancer. 2004 Aug 10;111(1):138-46. [DOI:10.1002/ijc.20209] [PMID]
31. D'Cruz AK, Robinson MH, Biel MA. mTHPC-mediated photodynamic therapy in patients with advanced, incurable head and neck cancer: a multicenter study of 128 patients. Head Neck. 2004 Mar;26(3):232-40. [DOI:10.1002/hed.10372] [PMID]
32. Lou PJ, Jäger HR, Jones L, Theodossy T, Bown SG, Hopper C. Interstitial photodynamic therapy as salvage treatment for recurrent head and neck cancer. Br J Cancer. 2004 Aug 2;91(3):441-6. [DOI:10.1038/sj.bjc.6601993] [PMID] [PMCID]
33. Biel MA. Photodynamic therapy treatment of early oral and laryngeal cancers. Photochem Photobiol. 2007 Sep-Oct;83(5):1063-8. [DOI:10.1111/j.1751-1097.2007.00153.x] [PMID]
34. Agostinis P, Berg K, Cengel KA, Foster TH, Girotti AW, Gollnick SO, Hahn SM, Hamblin MR, Juzeniene A, Kessel D, Korbelik M, Moan J, Mroz P, Nowis D, Piette J, Wilson BC, Golab J. Photodynamic therapy of cancer: an update. CA Cancer J Clin. 2011 Jul-Aug;61(4):250-81. [DOI:10.3322/caac.20114] [PMID] [PMCID]
35. Abdel Gaber SA. Photodynamic Diagnosis and Therapy for Oral Potentially Malignant Disorders and Cancers. In: Al-Moustafa AE, editor. Development of Oral Cancer: Risk Factors and Prevention Strategies. Switzerland: Springer; Cham; 2017. p. 147-75. [DOI:10.1007/978-3-319-48054-1_10]
36. Azizi A, Lawaf S. Photodynamic therapy (PDT). J Res Dent Maxillofac Sci. 2021; 6 (1) :1-3.
37. Hopper C. Photodynamic Therapy for the Treatment of Oral Cancer. [Thesis on the Internet]. London: University College London; 2006. [cited 2021 Feb 1]. Available from: https://core.ac.uk/download/pdf/29141844.pdf.

Add your comments about this article : Your username or Email:

Send email to the article author

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© 2022 CC BY-NC 4.0 | Journal of Research in Dental and Maxillofacial Sciences

Designed & Developed by : Yektaweb