Journal of Research in Dental
and Maxillofacial Sciences
Volume 11, Issue 1 (3-2026)
J Res Dent Maxillofac Sci 2026, 11(1): 8-21 |
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Ethics code: IRCT20101204005305N22
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Shahbazpey S, Mohammadi M, Lashkarizadeh N. Comparative Efficacy of Acellular Dermal Matrix with and without Injectable Platelet-Rich Fibrin, and Free Gingival Graft for Enhancement of Peri-Implant Keratinized Gingiva Width: A Randomized Controlled Clinical Trial. J Res Dent Maxillofac Sci 2026; 11 (1) :8-21
URL: http://jrdms.dentaliau.ac.ir/article-1-1274-en.html
URL: http://jrdms.dentaliau.ac.ir/article-1-1274-en.html
1- Department of Periodontics, School of Dentistry, Kerman University of Medical Sciences, Shafa St, Kerman, 7616913555, Iran
2- Department of Periodontics, School of Dentistry, Kerman University of Medical Sciences, Shafa St, Kerman, 7616913555, Iran ,Mmohammadi28@yahoo.com
2- Department of Periodontics, School of Dentistry, Kerman University of Medical Sciences, Shafa St, Kerman, 7616913555, Iran ,
Abstract: (46 Views)
Abstract
Background and Aim: This study compared the efficacy of acellular dermal matrix (ADM) with and without injectable platelet-rich fibrin (iPRF) and free gingival graft (FGG) for the enhancement of peri-implant keratinized gingiva width (KGW).
Materials and Methods: In this randomized controlled clinical trial, 36 dental implants with KGW<2 mm were randomly assigned to 3 groups (n=12) for enhancement of KGW with FGG alone (control group), ADM alone (AlloDerm), and iPRF-impregnated ADM (AlloDerm). KGW, pain by using a visual analog scale (VAS), and graft shrinkage percentage (reduction in height and surface area of the graft) were assessed 3 months after surgery, and compared by one-way ANOVA and Sidak test (alpha=0.05).
Results: A significant increase in peri-implant KGW was observed after treatment in all three groups (P<0.001). FGG caused a significantly greater increase in KGW than the other two groups (P<0.001). Graft shrinkage was significantly lower in the FGG group than other groups (P<0.05). Postoperative pain was significantly lower in the ADM/iPRF than the FGG (P<0.001) and ADM (P=0.002) groups. Postoperative pain in the ADM group was significantly lower than that in the FGG group (P=0.008). No other significant differences were found (P>0.05).
Conclusion: All three tested methods significantly increased the peri-implant KGW. Although FGG was the most effective for the enhancement of KGW, it was associated with the highest postoperative pain level. IPRF-impregnated ADM may be considered as an acceptable, less invasive, and less painful approach for patients not consenting to FGG, although it had no significant difference with ADM alone.
Background and Aim: This study compared the efficacy of acellular dermal matrix (ADM) with and without injectable platelet-rich fibrin (iPRF) and free gingival graft (FGG) for the enhancement of peri-implant keratinized gingiva width (KGW).
Materials and Methods: In this randomized controlled clinical trial, 36 dental implants with KGW<2 mm were randomly assigned to 3 groups (n=12) for enhancement of KGW with FGG alone (control group), ADM alone (AlloDerm), and iPRF-impregnated ADM (AlloDerm). KGW, pain by using a visual analog scale (VAS), and graft shrinkage percentage (reduction in height and surface area of the graft) were assessed 3 months after surgery, and compared by one-way ANOVA and Sidak test (alpha=0.05).
Results: A significant increase in peri-implant KGW was observed after treatment in all three groups (P<0.001). FGG caused a significantly greater increase in KGW than the other two groups (P<0.001). Graft shrinkage was significantly lower in the FGG group than other groups (P<0.05). Postoperative pain was significantly lower in the ADM/iPRF than the FGG (P<0.001) and ADM (P=0.002) groups. Postoperative pain in the ADM group was significantly lower than that in the FGG group (P=0.008). No other significant differences were found (P>0.05).
Conclusion: All three tested methods significantly increased the peri-implant KGW. Although FGG was the most effective for the enhancement of KGW, it was associated with the highest postoperative pain level. IPRF-impregnated ADM may be considered as an acceptable, less invasive, and less painful approach for patients not consenting to FGG, although it had no significant difference with ADM alone.
Type of Study: Original article |
Subject:
Periodontology
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