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Volume 11, Issue 2 (6-2026)                   J Res Dent Maxillofac Sci 2026, 11(2): 156-163 | Back to browse issues page

Ethics code: IR.IAU.DENTAL.REC.1398.022
Clinical trials code: invitro study

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Farzandi N, Farnia F, Aghaei S, Saati K, Tavassoli-Hojjati S. Effect of Several Iron Drops with Different Dilutions on Color and Structure of Primary Teeth. J Res Dent Maxillofac Sci 2026; 11 (2) :156-163
URL: http://jrdms.dentaliau.ac.ir/article-1-1107-en.html
1- Department of Pediatric Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
2- Department of Restorative Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
3- Department of Pediatric Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran , tavasolisara@yahoo.com
Abstract:   (14 Views)
Background and Aim: Discoloration of primary teeth caused by iron supplementation often discourages parents from using it for their children. This study aimed to evaluate the effects of Sideral iron drops with a sucrosomial structure, Irofent iron drops, and Irofent diluted with natural apple juice on the color and structural integrity of primary tooth enamel.   
Materials and Methods: In this in vitro study, 45 sound primary anterior teeth were randomly divided into three groups of 15 for treatment with Sideral, Irofent, and a mixture of Irofent and natural apple juice. A digital spectrophotometer measured the initial tooth color. Teeth were immersed in their respective iron solutions for 5 minutes at 37°C, rinsed with distilled water, and their final color was recorded. One sample from each group underwent scanning electron microscopy (SEM) to assess surface structural changes. Quantitative data were analyzed using one-way ANOVA. P<0.05 was considered significant.   
Results: Color change (∆E) was significantly greater in the Irofent group compared to Irofent–apple juice and Sideral groups (P<0.001). The Irofent–apple juice group showed significantly more discoloration than Sideral (P<0.001). SEM revealed enamel surface cracks in Irofent and Irofent–apple juice groups; whereas the Sideral group showed no defects.
Conclusion: Sideral iron drops did not cause significant discoloration or structural damage to primary enamel in this in vitro study. Combining Irofent with natural apple juice may reduce its adverse effects.
 
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Type of Study: Original article | Subject: pediatric

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