<?xml version="1.0" encoding="utf-8"?>
<journal>
<title>Journal of Research in Dental and Maxillofacial Sciences</title>
<title_fa></title_fa>
<short_title>J Res Dent Maxillofac Sci</short_title>
<subject>Medical Sciences</subject>
<web_url>http://jrdms.dentaliau.ac.ir</web_url>
<journal_hbi_system_id>1</journal_hbi_system_id>
<journal_hbi_system_user>admin</journal_hbi_system_user>
<journal_id_issn>2588-4166</journal_id_issn>
<journal_id_issn_online>2383-2754</journal_id_issn_online>
<journal_id_pii></journal_id_pii>
<journal_id_doi>10.61882/jrdms</journal_id_doi>
<journal_id_iranmedex></journal_id_iranmedex>
<journal_id_magiran></journal_id_magiran>
<journal_id_sid></journal_id_sid>
<journal_id_nlai></journal_id_nlai>
<journal_id_science></journal_id_science>
<language>en</language>
<pubdate>
	<type>jalali</type>
	<year>1404</year>
	<month>9</month>
	<day>1</day>
</pubdate>
<pubdate>
	<type>gregorian</type>
	<year>2025</year>
	<month>12</month>
	<day>1</day>
</pubdate>
<volume>10</volume>
<number>4</number>
<publish_type>online</publish_type>
<publish_edition>1</publish_edition>
<article_type>fulltext</article_type>
<articleset>
	<article>


	<language>en</language>
	<article_id_doi></article_id_doi>
	<title_fa></title_fa>
	<title>In Vitro Efficacy of Potassium Iodide and Glutathione in Masking Silver Diamine Fluoride-Induced Staining in Primary Molars</title>
	<subject_fa>Restorative Dentistry</subject_fa>
	<subject>Restorative Dentistry</subject>
	<content_type_fa>Original article</content_type_fa>
	<content_type>Original article</content_type>
	<abstract_fa></abstract_fa>
	<abstract>&lt;div style=&quot;text-align: justify;&quot;&gt;&lt;span style=&quot;font-size:13pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;&lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot; verdana=&quot;&quot;&gt;&lt;span style=&quot;color:#2e74b5&quot;&gt;Background and Aim&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;b&gt;&lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot; verdana=&quot;&quot;&gt;&lt;span style=&quot;color:#2e74b5&quot;&gt;:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/b&gt; &lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot; verdana=&quot;&quot;&gt;Silver diamine fluoride (SDF) is an effective cariostatic agent used in minimally invasive dentistry. However, one major drawback of SDF is dark staining after its application, limiting its clinical use. This study quantified the color change associated with the application of SDF on extracted carious primary molars, the potential masking effects of potassium iodide (KI) and glutathione, and the effect of aging on their masking effect. &amp;nbsp;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&amp;nbsp;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:13pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;&lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot; verdana=&quot;&quot;&gt;&lt;span style=&quot;color:#2e74b5&quot;&gt;Materials and Methods: &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot; verdana=&quot;&quot;&gt;In this in vitro experimental study, 45 extracted primary carious molars with International Caries Detection Assessment System scores 5 and 6 were collected, cleaned of debris, and stored in distilled water until use. Previously restored teeth and those with pulpal involvement were excluded. The selected teeth were randomly categorized into 3 groups (n=15) for the application of SDF (group 1), SDF+ KI (group 2), and SDF+ glutathione (group 3). Test materials were applied, and images were captured immediately and on day 14. The mean gray values were calculated using Image J software and tabulated. Statistical analysis was done using paired t-test, one-way ANOVA, and Tukey&amp;rsquo;s test (alpha=0.05). &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&amp;nbsp;&amp;nbsp;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:13pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;&lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot; verdana=&quot;&quot;&gt;&lt;span style=&quot;color:#2e74b5&quot;&gt;Results: &lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/b&gt;&lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot; verdana=&quot;&quot;&gt;&lt;span style=&quot;color:#0e101a&quot;&gt;KI and glutathione were able to mask the staining of SDF compared to SDF alone. SDF+ KI showed the least staining compared to other groups after a 14-day period, which was statistically significant (P&lt;0.05).&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot;Verdana&quot;,sans-serif&quot;&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&lt;span style=&quot;font-size:13pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span new=&quot;&quot; roman=&quot;&quot; style=&quot;font-family:&quot; times=&quot;&quot;&gt;&lt;b&gt;&lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot; verdana=&quot;&quot;&gt;&lt;span style=&quot;color:#2e74b5&quot;&gt;Conclusion:&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/b&gt; &lt;span style=&quot;font-size:9.0pt&quot;&gt;&lt;span style=&quot;line-height:110%&quot;&gt;&lt;span style=&quot;font-family:&quot; verdana=&quot;&quot;&gt;&lt;span style=&quot;color:#0e101a&quot;&gt;Within the study limitations, KI can be considered as a potential masking agent that can overcome the black staining caused by SDF, which is the main barrier to parental acceptance of SDF treatment.&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;/span&gt;&lt;br&gt;
&amp;nbsp;&lt;/div&gt;</abstract>
	<keyword_fa></keyword_fa>
	<keyword>Dental Caries, Glutathione, Potassium Iodide, Tooth, Deciduous, Silver Compounds</keyword>
	<start_page>321</start_page>
	<end_page>329</end_page>
	<web_url>http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-1777-1&amp;slc_lang=en&amp;sid=1</web_url>


<author_list>
	<author>
	<first_name>Deepthi Nirmal</first_name>
	<middle_name></middle_name>
	<last_name>Gavarraju</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>drdeepthipedo@sids.ac.in</email>
	<code>100319475328460016121</code>
	<orcid>100319475328460016121</orcid>
	<coreauthor>Yes
</coreauthor>
	<affiliation>Department of Pediatric and Preventive Dentistry, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, India</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Jahnavi</first_name>
	<middle_name></middle_name>
	<last_name>Chalasani</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>chalasanijahnavi@gmail.com</email>
	<code>100319475328460016122</code>
	<orcid>0009-0002-0893-2868</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Sibar Institute of Dental Sciences, Takkellapadu, Guntur, India</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Sai Sankar</first_name>
	<middle_name></middle_name>
	<last_name>A.J</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>saisamata@gmail.com</email>
	<code>100319475328460016123</code>
	<orcid>100319475328460016123</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Pediatric and Preventive Dentistry, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, India</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Raja Satish</first_name>
	<middle_name></middle_name>
	<last_name>Prathigudupu</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>rajasatish79@gmail.com</email>
	<code>100319475328460016124</code>
	<orcid>100319475328460016124</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Department of Oral &amp; Maxillofacial Surgery, Sibar Institute of Dental Sciences, Takkellapadu, Guntur, India</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


	<author>
	<first_name>Dhanush</first_name>
	<middle_name></middle_name>
	<last_name>Ramayanapu</last_name>
	<suffix></suffix>
	<first_name_fa></first_name_fa>
	<middle_name_fa></middle_name_fa>
	<last_name_fa></last_name_fa>
	<suffix_fa></suffix_fa>
	<email>dk.ramayanapu@gmail.com</email>
	<code>100319475328460016125</code>
	<orcid>0009-0003-1493-5149</orcid>
	<coreauthor>No</coreauthor>
	<affiliation>Sibar Institute of Dental Sciences, Takkellapadu, Guntur, India</affiliation>
	<affiliation_fa></affiliation_fa>
	 </author>


</author_list>


	</article>
</articleset>
</journal>
