Journal of Research in Dental and Maxillofacial Sciences

en Comparative Effects of Root Canal Irrigation with Sodium Hypochlorite and Super-oxidized Water on Post-Endodontic Pain in Single-Canal Teeth: A Clinical Trial Endodontics Endodontics Randomized Clinical Trial <div style="text-align: justify;">Background and Aim: This study aimed to compare the effects of root canal irrigation with sodium hypochlorite (NaOCl) and super-oxidized water on post-endodontic pain in single-canal teeth.   Materials and Methods: This double-blind randomized clinical trial was conducted on 72 patients with irreversible pulpitis of single-canal teeth. The patients were randomly assigned to two groups (n=36) for root canal irrigation with either 1% NaOCl or 50% super-oxidized water during endodontic treatment. The root canals were instrumented by the step-back technique with a minimum and maximum apical preparation size of 30 and 50, respectively, and flaring by 5 files larger than the master apical file. Patients' pain level was quantified at 6, 12, 24, 48, and 72 hours, and 7 days postoperatively using a visual analog scale (VAS). Root canal treatments were accomplished in two sessions, and calcium hydroxide was applied as intracanal medicament. Data were analyzed by the Mann-Whitney test (alpha=0.05).  Results: At 12 hours postoperatively, the pain score was significantly higher in the NaOCl group than the super-oxidized water group (P=0.043). The pain score gradually decreased in both groups after 12 hours with no pain recorded at 7 days. The difference in pain score between the two groups was not significant at any other time point (P>0.05). Conclusion: The present results revealed significantly lower level of pain at 12 hours post-treatment of single-canal teeth in root canal irrigation with super-oxidized water.  </div> Root Canal Irrigants, Root Canal Therapy, Sodium Hypochlorite, Superoxidized Water, Pain 243 249 http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-1380-1&slc_lang=en&sid=1 Sohrab TourSavadkouhi s_savadkouhi@yahoo.com 100319475328460013602 100319475328460013602 No Dental Material Research Center, Dental School, Islamic Azad University of Medical Sciences, Tehran, Iran Seyed Amirmasoud Mousavi masood975@yahoo.com 100319475328460013603 100319475328460013603 No Department of Oral and Maxillofacial Surgery, School of Dentistry, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran. Ehsan Asnaashari Ehsan_dmd@yahoo.com 100319475328460013604 100319475328460013604 No Endodontic Department, Dental School, Islamic Azad University of Medical Sciences, Tehran, Iran Mohammadsadegh Ahmadi m.sadegh.ahmadi.98@gmail.com 100319475328460013605 100319475328460013605 No Dentist, Dental School, Islamic Azad University of Medical Sciences, Tehran, Iran koosha Khajehmougahi khajehmougahikousha@gmail.com 100319475328460013606 0009-0000-4377-3634 Yes Dentist, Dental School, Islamic Azad University of Medical Sciences, Tehran, Iran