Journal of Research in Dental and Maxillofacial Sciences

en Panoramic Radiographic Features of Patients with Acute Leukemia and Lymphoma who Are Candidates for Hematopoietic Stem Cell Transplantation Oral medicine Oral medicine Original article Original article <div style="text-align: justify;">Background and Aim: Hematopoietic malignancies like leukemia and lymphoma may present several complications. This study aimed to evaluate the panoramic radiographic features of patients with acute leukemia and lymphoma who are candidates for hematopoietic stem cell transplantation (HSCT). Materials and Methods: In this cross-sectional study, 63 panoramic radiographs of HSCT candidates (25 females, 38 males, between 16-75 years) and 62 healthy individuals (25 females, 37 males, between 16-73 years) were evaluated in Shiraz, Iran. Osteoporosis, pathological radiolucencies, pathological calcifications, cortical bone thickness, periodontal disease, condylar degeneration, and other alveolar bone findings were recorded. Data were analyzed by the Chi-square, Fisher’s exact, and Mann-Whitney U tests (alpha=0.05).  Results: The thickness of nasal floor cortical bone, mandibular inferior cortex, and mandibular canal cortex was significantly lower in the patient group than the healthy group (P<0.05). Other abnormalities such as changes in periodontal ligament width, lamina dura thickness, and condylar degeneration were also more prevalent in HSCT patients compared to healthy controls (P≤0.05). Conclusion: It appears that panoramic views provide reliable information for detection of osteopenia and osteoporosis in HSCT patients. This may reduce the use of expensive and invasive diagnostic workups with radiation exposure to detect low bone density in this group of compromised patients.  </div> Jaw Abnormalities, Radiography, Panoramic, Hematopoietic Stem Cell Transplantation 35 42 http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-1254-1&slc_lang=en&sid=1 Azita Azad azitaazad56@gmail.com 100319475328460011829 0000000210734134 No Oral and Dental Disease Research Center, Department of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran Abdolaziz Haghnegahdar ahagh@sums.ac.ir 100319475328460011830 0000000253289878 No Department of Oral and Maxillofacial Radiology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran Janan Ghapanchi ghabanj@sums.ac.ir 100319475328460011831 0000000217807412 No Oral and Dental Disease Research Center, Department of Oral and Maxillofacial Medicine, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran Ali Hakimelahi alihakimelahi@gmail.com 100319475328460011832 0000000237736842 No Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran Zahra Mansouri mansouriz9085@gmail.com 100319475328460011833 0000000349673970 Yes Student Research Committee, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran