Journal of Research in Dental and Maxillofacial Sciences

en Effect of Pistacia lentiscus Extract on Dentin Remineralization: An In Vitro Study Oral medicine Oral medicine Original article Original article <div style="text-align: justify;">Background and Aim: This study aimed to assess the efficacy of Pistacia lentiscus (P. lentiscus) extract for dentin remineralization. Materials and Methods: This in vitro experimental study evaluated 45 extracted sound human premolars; pH cycling was performed to assess the effect of 10% P. lentiscus extract on dentin remineralization. The samples were randomly assigned to three groups of 1000 ppm sodium fluoride (NaF) solution, 10% P. lentiscus extract, and deionized water. To induce dentinal lesions, the teeth were immersed in a demineralizing solution at 37°C for 96 hours. The demineralized samples were then subjected to pH cycling for 14 days, and then underwent the Vickers microhardness test and scanning electron microscopic (SEM) assessment. Data were analyzed by repeated-measures ANOVA. Results: The mean microhardness in the NaF group was significantly higher than that in the extract and control groups after 14 days (P<0.05). SEM assessment after demineralization indicated tubular obstruction in the extract and NaF groups. However, after 14 days, the sealing of dentinal tubules in the extract group was greater than that in the NaF group. Conclusion: P. lentiscus extract can serve as a suitable organic compound for dentinal tubule occlusion as well as non-invasive and conservative treatment of dentin hypersensitivity (DH).</div> Dentin sensitivity, Dentin Desensitizing Agents, Pistacia lentiscus, Microscopy, Electron, Scanning 49 56 http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-974-1&slc_lang=en&sid=1 Azam Valian avalian14@yahoo.com 100319475328460011385 100319475328460011385 No Department of Restorative Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran Ali Tareh ali_tareh@yahoo.com 100319475328460011386 100319475328460011386 No Private Office, Tehran, Iran Malek Zarei M.Zarei@sbmu.ac.ir 100319475328460011387 100319475328460011387 No Department of Pharmacology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran Samaneh Gholami Mandali sama.ghlm72@gmail.com 100319475328460011388 100319475328460011388 Yes Department of Restorative Dentistry, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran