en Radiology Radiology Original article Original article <div style="text-align: justify;"><span style="font-size:13pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><b><span style="font-size:9.0pt"><span style="font-family:&quot;Verdana&quot;,sans-serif"><span style="color:#2e74b5">Background and Aim</span></span></span></b><b><span style="font-size:9.0pt"><span style="font-family:&quot;Verdana&quot;,sans-serif"><span style="color:#2e74b5">:</span></span></span></b> <span style="font-size:9.0pt"><span style="font-family:&quot;Verdana&quot;,sans-serif">Although soft tissue calcifications are relatively common and are commonly seen on panoramic radiographs, few studies have reported their causes. Therefore, the present study was conducted to investigate the relationship between systemic diseases and ectopic calcifications. </span></span></span></span><br> <span style="font-size:13pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><b><span style="font-size:9.0pt"><span style="font-family:&quot;Verdana&quot;,sans-serif"><span style="color:#2e74b5">Materials and Methods: </span></span></span></b><span style="font-size:9.0pt"><span style="font-family:&quot;Verdana&quot;,sans-serif">In this descriptive study, the study population included patients referred to the Radiology Department of two specialized dental clinics in Ilam and Kermanshah cities from 2020-2021. A total of 1000 participants were voluntarily examined. The collected data were analyzed using the correlation and logistic regression tests.&nbsp; </span></span></span></span><br> <span style="font-size:13pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><b><span style="font-size:9.0pt"><span style="font-family:&quot;Verdana&quot;,sans-serif"><span style="color:#2e74b5">Results: </span></span></span></b><span style="font-size:9.0pt"><span style="font-family:&quot;Verdana&quot;,sans-serif">The prevalence of calcifications was 39.4% in Ilam and 27.6% in Kermanshah. Also, the results showed that there was a significant relationship between systemic diseases and calcifications (P<0.05). The correlation coefficient between systemic diseases and calcifications was r=0.76 (P=0.02) in Ilam, and r=0.84 (P=0.00) in Kermanshah. Age and sex could not predict calcifications (P>0.05).</span></span></span></span><br> <span style="font-size:13pt"><span style="font-family:&quot;Times New Roman&quot;,serif"><b><span style="font-size:9.0pt"><span style="font-family:&quot;Verdana&quot;,sans-serif"><span style="color:#2e74b5">Conclusion:</span></span></span></b> <span style="font-size:9.0pt"><span style="font-family:&quot;Verdana&quot;,sans-serif">Based on the findings, calcifications on panoramic radiographs may serve as a predictor for presence of systemic diseases. </span></span></span></span><br> &nbsp;</div> Prevalence, Calcification, Physiologic, Calcinosis, Radiography, Panoramic, Iran 43 48 http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-966-1&slc_lang=en&sid=1 Khadijeh Abdal abdal-kh@medilam.ac.ir 100319475328460011834 100319475328460011834 No Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, Ilam University of Medical Sciences, Ilam, Iran Azar Yari yari-a@medilam.ac.ir 100319475328460011835 100319475328460011835 No Faculty of Dentistry, Ilam University of Medical Sciences, Ilam, Iran Mahtab Bonyadi bonyadi-m@medilam.ac.ir 100319475328460011837 100319475328460011837 No Non-Communicable Diseases Research Center, Ilam University of Medical Sciences,Ilam,Iran Elham Shafiei shafiei-e@medilam.ac.ir 100319475328460011838 0000000156895235 Yes Clinical Research Development Unit, Ayatollah Taleghani Hospital, Ilam University of Medical Sciences, Ilam, Iran