en Oral & maxillofacial surgery Oral & maxillofacial surgery Original article Original article <div> <table align="center" hspace="0" vspace="0"> <tbody> <tr> <td style="padding: 0in 12px; text-align: justify;" valign="top"><span style="font-size:13pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:9.0pt"><span style="font-family:" verdana=""><span style="color:#2e74b5">Background and Aim</span></span></span></b><b><span style="font-size:9.0pt"><span style="font-family:" verdana=""><span style="color:#2e74b5">:</span></span></span></b><b> </b><span style="font-size:9.0pt"><span style="font-family:" verdana="">Achieving adequate pulpal anesthesia could be challenging in mandibular molars. There are some disagreements about the success rate of local infiltration anesthesia with articaine as primary injection. Therefore, the aim of this study was to assess the efficacy of 4% articaine lingual subperiosteal injection as the primary injection for permanent mandibular second molars in comparison with inferior alveolar nerve block (IANB). &nbsp;</span></span></span></span><br> <span style="font-size:13pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:9.0pt"><span style="font-family:" verdana=""><span style="color:#2e74b5">Materials and Methods:</span></span></span></b><span style="font-size:9.0pt"><span style="font-family:" verdana=""> Fifteen healthy adult volunteers participated in this study. A randomized, split-mouth, single-blind design was used to allocate each side of the mandible in each patient to the test or control group. On the test side, lingual subperiosteal injection with 4% articaine and 1:100,000 epinephrine was<br> performed for the mandibular second molar; whereas, in the control group, an IANB with 2% lidocaine and 1:80,000 epinephrine was administered. Electric pulp testing was done at baseline, and also at 5, 8, 11, 15, 20, 25, 30, 45, 60, 75, and 90 minutes after injection. Statistical analysis was carried out using t-test and Chi-square test. </span></span></span></span><br> <span style="font-size:13pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:9.0pt"><span style="font-family:" verdana=""><span style="color:#2e74b5">Results</span></span></span></b><span style="font-size:9.0pt"><span style="font-family:" verdana=""><span style="color:#2e74b5">:</span></span></span> <span style="font-size:9.0pt"><span style="font-family:" verdana="">The success rate of IANB was significantly higher than that of lingual subperiosteal injection (P=0.0001). The difference in the onset of action between the two groups was significant (P<0.05). Anesthesia duration was 61.0&plusmn;28.0 minutes in IANB group and 10.2&plusmn;12.4 minutes in lingual subperiosteal injection group, with a significant difference between them (P<0.01). </span></span></span></span><br> <span style="font-size:13pt"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:9.0pt"><span style="font-family:" verdana=""><span style="color:#2e74b5">Conclusion:</span></span></span></b> <span style="font-size:9.0pt"><span style="font-family:" verdana="">IANB with 2% lidocaine is preferable to 4% articaine lingual subperiosteal injection due to its superior success rate, faster onset of action, and longer duration of effect. </span></span></span></span></td> </tr> <tr> <td style="padding: 0in 12px; text-align: justify;" valign="top"><p></p></td> </tr> </tbody> </table> </div> Anesthesia, Dental, Anesthesia, Local, Mandibular Nerve 119 124 http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-874-1&slc_lang=en&sid=1 E Esnaashari ehsan_dmd@yahoo.com 100319475328460010395 100319475328460010395 No Department of Endodontics, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran SH Mirzaei shadi.mirzaei91@yahoo.com 100319475328460010396 100319475328460010396 No Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran AA Moshari amirabbas.moshari@gmail.com 100319475328460010397 100319475328460010397 No Department of Endodontics, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran P Razavi porazavi1@yahoo.com 100319475328460010398 100319475328460010398 Yes Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran