Journal of Research in Dental and Maxillofacial Sciences

en Comparative Efficacy of Acellular Dermal Matrix with and without Injectable Platelet-Rich Fibrin, and Free Gingival Graft for Enhancement of Peri-Implant Keratinized Gingiva Width: A Randomized Controlled Clinical Trial Periodontology Periodontology Original article Original article <div style="text-align: justify;">Abstract Background and Aim: This study compared the efficacy of acellular dermal matrix (ADM) with and without injectable platelet-rich fibrin (iPRF) and free gingival graft (FGG) for the enhancement of peri-implant keratinized gingiva width (KGW).     Materials and Methods: In this randomized controlled clinical trial, 36 dental implants with KGW<2 mm were randomly assigned to 3 groups (n=12) for enhancement of KGW with FGG alone (control group), ADM alone (AlloDerm), and iPRF-impregnated ADM (AlloDerm). KGW, pain by using a visual analog scale (VAS), and graft shrinkage percentage (reduction in height and surface area of the graft) were assessed 3 months after surgery, and compared by one-way ANOVA and Sidak test (alpha=0.05).     Results: A significant increase in peri-implant KGW was observed after treatment in all three groups (P<0.001). FGG caused a significantly greater increase in KGW than the other two groups (P<0.001). Graft shrinkage was significantly lower in the FGG group than other groups (P<0.05). Postoperative pain was significantly lower in the ADM/iPRF than the FGG (P<0.001) and ADM (P=0.002) groups. Postoperative pain in the ADM group was significantly lower than that in the FGG group (P=0.008). No other significant differences were found (P>0.05). Conclusion: All three tested methods significantly increased the peri-implant KGW. Although FGG was the most effective for the enhancement of KGW, it was associated with the highest postoperative pain level. IPRF-impregnated ADM may be considered as an acceptable, less invasive, and less painful approach for patients not consenting to FGG, although it had no significant difference with ADM alone.  </div> Acellular Dermis, Alloderm, Dental Implants, Platelet-Rich Fibrin 8 21 http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-2549-6&slc_lang=en&sid=1 Shahin Shahbazpey sh.shahbazpey@gmail.com 100319475328460016451 100319475328460016451 No Department of Periodontics, School of Dentistry, Kerman University of Medical Sciences, Shafa St, Kerman, 7616913555, Iran Mohammad Mohammadi Mmohammadi28@yahoo.com 100319475328460016452 100319475328460016452 Yes Department of Periodontics, School of Dentistry, Kerman University of Medical Sciences, Shafa St, Kerman, 7616913555, Iran Nazila Lashkarizadeh Nazilalashkarizadeh@gmail.com 100319475328460016453 100319475328460016453 No Department of Periodontics, School of Dentistry, Kerman University of Medical Sciences, Shafa St, Kerman, 7616913555, Iran