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J Res Dent Maxillofac Sci 2021, 6(1): 1-3 |
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Azizi A, Lawaf S. Photodynamic therapy (PDT). J Res Dent Maxillofac Sci 2021; 6 (1) :1-3
URL: http://jrdms.dentaliau.ac.ir/article-1-303-en.html
URL: http://jrdms.dentaliau.ac.ir/article-1-303-en.html
1- Professor, Oral Medecine Dept, Faculty of Dentistry,Tehran Medical Sciences, Islamic Azad University, Tehran, Iran , drarashazizi@yahoo.com
2- Associate Professor, Prosthodontics Dept, Member ship of Dental Material Research Center, Faculty of Dentistry,Tehran Medical Sciences
2- Associate Professor, Prosthodontics Dept, Member ship of Dental Material Research Center, Faculty of Dentistry,Tehran Medical Sciences
Abstract: (2333 Views)
Photodynamic therapy (PDT) is a comparatively novel therapeutic method involving a safe light source and a light-sensitive substance, termed as photosensitizers (PSs), such as methylene blue (MB), toluidine blue (TBO), sulfonated aluminum phthalocyanine, chlorine derivatives, nontoxic indocyanine green (ICG), and curcumin (CUR). (1) The combination of a nontoxic PS with low-intensity visible light in the presence of oxygen develops reactive oxygen species (ROS) that are toxic and can cause oxidative damage to microorganisms and tumor cells. (2-4) PSs do not induce cytotoxicity but are activated by laser irradiation at a proper wavelength and develop ROS. (5,6)
Type of Study: Original article |
Subject:
Oral medicine
References
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