Volume 7, Issue 4 (10-2022)                   J Res Dent Maxillofac Sci 2022, 7(4): 226-232 | Back to browse issues page


XML Print


1- Department of Periodontology, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran , dr.ssalimzade@gmail.com
2- Department of Periodontology, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran
Abstract:   (941 Views)
Background and Aim: Considering the efficacy of platelet-rich fibrin (PRF) in enhancement of healing by releasing growth factors, this study aimed to assess the efficacy of PRF application as a protective barrier right beneath the sinus membrane on the Schneiderian membrane thickness following sinus floor augmentation.  
Materials and Methods: This randomized controlled split-mouth clinical trial was conducted on 18 patients (36 sinuses) who required bilateral sinus floor augmentation. Two patients (n=4 sinuses) were excluded due to chronic sinusitis, and one patient due to perioperative sinus membrane perforation. Fifteen patients (n=30 sinuses) were finally assessed. In the test side, PRF membrane was placed beneath the Schneiderian membrane while augmentation was performed without a PRF membrane in the control side. Cone-beam computed tomography (CBCT) scans were taken preoperatively, and at 1 week and 2 months postoperatively, and the Schneiderian membrane thickness was compared at the two sides using ANOVA and a post-hoc test.
Results: The mean membrane thickness was 1.85±0.85 mm in the control and 2.17±0.87 mm in the test group before the intervention (P=0.6). At 1 week, the mean thickness was 2.45±1.22 in the control and 3.77±1.42 mm in the case group (P=0.2). At 2 months, the mean thickness was 2.54±1.66 mm in the control and 1.71±1.31 mm in the test group (P=0.2). ANOVA showed no significant difference between the two groups at any time point (P>0.05).
Conclusion: Application of PRF under the Schneiderian membrane in sinus floor augmentation had no significant effect on the Schneiderian membrane thickness.
Full-Text [PDF 753 kb]   (491 Downloads) |   |   Full-Text (HTML)  (299 Views)  
Type of Study: Original article | Subject: Periodontology

References
1. Ali S, Bakry SA, Abd-Elhakam H. Platelet-Rich Fibrin in Maxillary Sinus Augmentation: A Systematic Review. J Oral Implantol. 2015 Dec;41(6):746-53. [DOI:10.1563/AAID-JOI-D-14-00167] [PMID]
2. Chiapasco M, Zaniboni M, Rimondini L. Dental implants placed in grafted maxillary sinuses: a retrospective analysis of clinical outcome according to the initial clinical situation and a proposal of defect classification. Clin Oral Implants Res. 2008 Apr;19(4):416-28. [DOI:10.1111/j.1600-0501.2007.01489.x] [PMID]
3. Jung RE, Pjetursson BE, Glauser R, Zembic A, Zwahlen M, Lang NP. A systematic review of the 5-year survival and complication rates of implant-supported single crowns. Clin Oral Implants Res. 2008 Feb;19(2):119-30. [DOI:10.1111/j.1600-0501.2007.01453.x] [PMID]
4. Aguirre Zorzano LA, Rodríguez Tojo MJ, Aguirre Urizar JM. Maxillary sinus lift with intraoral autologous bone and B--tricalcium phosphate: histological and histomorphometric clinical study. Med Oral Patol Oral Cir Bucal. 2007 Nov 1;12(7):E532-6.
5. Janner SF, Caversaccio MD, Dubach P, Sendi P, Buser D, Bornstein MM. Characteristics and dimensions of the Schneiderian membrane: a radiographic analysis using cone beam computed tomography in patients referred for dental implant surgery in the posterior maxilla. Clin Oral Implants Res. 2011 Dec;22(12):1446-53. [DOI:10.1111/j.1600-0501.2010.02140.x] [PMID]
6. Makary C, Rebaudi A, Menhall A, Naaman N. Changes in Sinus Membrane Thickness After Lateral Sinus Floor Elevation: A Radiographic Study. Int J Oral Maxillofac Implants. 2016 Mar-Apr;31(2):331-7. [DOI:10.11607/jomi.4108] [PMID]
7. Watelet JB, Bachert C, Gevaert P, Van Cauwenberge P. Wound healing of the nasal and paranasal mucosa: a review. Am J Rhinol. 2002 Mar-Apr;16(2):77-84. [DOI:10.1177/194589240201600202] [PMID]
8. Elbaradie R, Ossman S, Eldibany R: Evaluation of platelet rich fibrin in sinus lifting with simultaneous implant placement. Alexandria Dent J 2015 July ;40(1):72-8. [DOI:10.21608/adjalexu.2015.58739]
9. Choukroun J, Adda F, Schoeffler C, Vervelle A. Une opportunité en paro-implantologie: Le PRF. Implantodontie2001;42:55-62.
10. Marx RE, Carlson ER, Eichstaedt RM, Schimmele SR, Strauss JE, Georgeff KR. Platelet-rich plasma: Growth factor enhancement for bone grafts. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Jun;85(6):638-46. [DOI:10.1016/S1079-2104(98)90029-4]
11. El-Sharkawy H, Kantarci A, Deady J, Hasturk H, Liu H, Alshahat M, Van Dyke TE. Platelet-rich plasma: growth factors and pro- and anti-inflammatory properties. J Periodontol. 2007 Apr;78(4):661-9. [DOI:10.1902/jop.2007.060302] [PMID]
12. Chandrun P, Sivadas A. Platelet-rich fibrin: Its role in periodontal regeneration. The Saudi Journal for Dental Research: 2014 ; 5(2):177-22. [DOI:10.1016/j.ksujds.2013.09.001]
13. Kumar YR, Mohanty S, Verma M, Kaur RR, Bhatia P, Kumar VR, Chaudhary Z. Platelet-rich fibrin: the benefits. Br J Oral Maxillofac Surg. 2016 Jan;54(1):57-61. [DOI:10.1016/j.bjoms.2015.10.015] [PMID]
14. Temmerman A, Cleeren GJ, Castro AB, Teughels W, Quirynen M. L-PRF for increasing the width of keratinized mucosa around implants: A split-mouth, randomized, controlled pilot clinical trial. J Periodontal Res. 2018 Oct; 53 (5):793-800. [DOI:10.1111/jre.12568] [PMID]

Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.