Journal of Research in Dental and Maxillofacial Sciences

en Comparative Efficacy of Triadent and Ora-Aid Mucoadhesive Patch for Treatment of Minor Aphthous Ulcers: A Clinical Trial Oral medicine Oral medicine Randomized Clinical Trial <div style="text-align: justify;">Background and Aim: This study aimed to compare the effects of Triadent (triamcinolone mucoadhesive paste) and Ora-Aid mucoadhesive patch on the severity of pain, burning sensation, and size of minor aphthous ulcers. Materials and Methods: This double-blind clinical trial was conducted on 40 patients with minor aphthous ulcers. The patients were randomly assigned to two groups (n=20) to use Triadent paste or Ora-Aid mucoadhesive patch (3 times/day). The severity of pain and burning sensation of patients was quantified by a visual analog scale (VAS). Size of lesions was also measured before, and at 3, 5, and 7 days after the treatment by using a graded paper placed next to the lesions. Data were analyzed by the t-test and the Mann-Whitney test (alpha=0.05).  Results: The mean reduction in lesion diameter at 3 days (compared with baseline) was significantly greater in the Ora-Aid than the Triadent group (P=0.000). However, the mean reduction in lesion diameter at 5 and 7 days was significantly greater in the Triadent group (P=0.000). The mean reduction in the severity of pain and burning sensation was significantly greater in the Ora-Aid group than the Triadent group at 3, 5, and 7 days (P=0.000). Conclusion: Both Triadent and Ora-Aid significantly decreased pain, burning sensation, and size of minor aphthous lesions. However, Triadent was significantly more effective for reduction of size of lesions while Ora-Aid was significantly more effective for reduction of pain and burning sensation.  </div> Stomatitis, Aphthous, Triamcinolone Acetonide, Humans 151 158 http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-1399-1&slc_lang=en&sid=1 Mohsen Barzegar 100319475328460012768 100319475328460012768 No Department of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran Hamidreza Ghadirian 100319475328460012769 100319475328460012769 No School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Zahra Roustaeizade Shooroki 100319475328460012770 100319475328460012770 No Department of Oral and Maxillofacial Medicine, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Mohammad Amin Yektaie 100319475328460012771 0009-0001-1797-9556 No Department of Oral and Maxillofacial Surgery, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. Adele Pouyafard a.pouyafard@gmail.com 100319475328460012772 100319475328460012772 Yes Department of Oral and Maxillofacial Medicine, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.