en Restorative Dentistry Restorative Dentistry Original article Original article <div style="text-align: justify;"><span style="font-size:13pt"><span style="line-height:99%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana=""><span style="color:#2e74b5">Background and Aim</span></span></span></span></b><b><span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana=""><span style="color:#2e74b5">:</span></span></span></span></b> <span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana="">Postoperative tooth hypersensitivity after restorative procedures is a common finding. Considering the obstruction of dentinal tubules following the use of dentin desensitizers, there are some concerns about the effects of desensitizers on the bond strength of bonding systems. This study aimed to assess the effect of a desensitizer on microshear bond strength (&micro;SBS) of two bonding systems.</span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="line-height:99%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana=""><span style="color:#2e74b5">Materials and Methods: </span></span></span></span></b><span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana="">In this in vitro study, 20 sound human molars were mesiodistally sectioned into halves, and the roots were cut at the cementoenamel junction. The samples (n=40) were then randomly divided into four groups (n=10): (I) Adper&trade; Single Bond 2, (II) Desensibilize desensitizing agent+ Adper&trade; Single Bond 2, (III) Single Bond Universal, and (IV) Desensibilize desensitizing agent + Single Bond Universal. Adhesives and desensitizing agents were applied according to the manufacturers&rsquo; instructions. Filtek Z250 composite cylinders were fabricated and bonded to dentin surfaces. The &micro;SBS of each sample was then measured. Data were analyzed by one-way ANOVA and a post-hoc test (P<0.05).</span></span></span>&nbsp;</span></span></span><br> <span style="font-size:13pt"><span style="line-height:99%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana=""><span style="color:#2e74b5">Results: </span></span></span></span></b><span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana="">A reduction in &micro;SBS was found following the application of desensitizing agent in combination with Adper^TM Single Bond 2 (P<0.05). The &micro;SBS increased when the desensitizing agent was applied in combination with Single Bond Universal. However, this difference was not significant (P</span></span></span><span style="font-size:9.0pt"><span style="line-height:99%"><span arial="" style="font-family:">˃</span></span></span><span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana="">0.05).</span></span></span></span></span></span><br> <span style="font-size:13pt"><span style="line-height:99%"><span new="" roman="" style="font-family:" times=""><b><span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana=""><span style="color:#2e74b5">Conclusion:</span></span></span></span></b> <span style="font-size:9.0pt"><span style="line-height:99%"><span style="font-family:" verdana="">Desensibilize desensitizing agent affected the dentinal tubule obstruction and decreased the &micro;SBS when used with Adper^TM Single Bond 2 total-etch system, while the &micro;SBS increased when it was used with Single Bond Universal adhesive. </span></span></span></span></span></span><br> &nbsp;</div> Dentin Desensitizing Agents, Shear Strength, Dentin-Bonding Agents 167 173 http://jrdms.dentaliau.ac.ir/browse.php?a_code=A-10-866-1&slc_lang=en&sid=1 Shaghayegh Shahidi maryam.rahimikhoob@gmail.com 100319475328460012742 100319475328460012742 No Private Dental Practice, Tehran, Iran. Solmaz Heidari heidari.soolmaz@gmail.com 100319475328460012743 100319475328460012743 No Department of Operative Dentistry, Dental Caries Prevention Research Center, Qazvin University of Medical Sciences, Qazvin, Iran. Maryam Rahimikhoob maryam.rahimikhoob@yahoo.com 100319475328460012744 100319475328460012744 No Department of Operative Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. Bahareh Farar spring199271@yahoo.com 100319475328460012745 100319475328460012745 No Department of Operative Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran. Shadab Safarzadeh Khosroshahi shadab.kh@gmail.com 100319475328460012746 0000000158738356 Yes Department of Operative Dentistry, Faculty of Dentistry, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.