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Showing 2 results for Alirezaei

S Alirezaei, E Razeghi, M Rezaie, N Moezi Ghadim, L Sabet Ghadam,
Volume 3, Issue 2 (Journal of Research in Dental & Maxillofacial Sciences Spring 2018)
Abstract

Background and Aim: Halitosis, candidiasis, and metallic taste are some of the oral complications in chronic renal failure patients undergoing dialysis. The aim was to evaluate the prevalence of oral manifestations and the related factors in hemodialysis patients at selected hospitals of Tehran in 2016.
Materials and Methods: This cross-sectional study was performed through observation, examination, interviewing, reviewing the medical records, and completing the information form. Oral manifestations were examined with indices of halitosis, metallic taste, and candidiasis. The presence of each indicator was considered as oral manifestations, and the measurement was standardized and performed by a student under the supervision of the respective professors. The training required for measurements was provided by the supervisor and the advisor. The reliability was measured in a seven-day pilot study. An organoleptic method was used to measure halitosis. The diagnosis of metallic taste and candidiasis was made through interviewing and observation, respectively.
Results: The study was performed on 250 patients (58.8% male and 41.2% female) with the mean age of 59 years (17 to 88 years). The average duration of dialysis was 62 months. Oral manifestations were present in 91.2% of patients. The most common oral manifestation was halitosis (90%), followed by metallic taste (12%), and candidiasis (10.8%). The incidence of candidiasis was higher in older patients and denture wearers (P≥0.05). Halitosis and metallic taste did not relate to the studied factors (P≥0.2 and ≥0.9).
Conclusion: The prevalence of oral manifestations in chronic kidney failure patients undergoing hemodialysis is high. Etiologic studies are recommended to understand the causes and to reduce the complications.
N Moezzi Ghadim, M Taghibakhsh, H Godarzi, N Liravinezhad Hoseini, S Alirezaei,
Volume 3, Issue 2 (Journal of Research in Dental & Maxillofacial Sciences Spring 2018)
Abstract

Background and aim: Reduction of oral pathogens is very important in the healing of oral ulcers and infections. The side effects of chemical drugs have attracted more attention to medicinal plants. The present study assessed the effect of clove, thyme, garlic, and cinnamon ethanolic extracts on the growth of Streptococcus mutans (S. mutans) and Lactobacillus by measuring the inhibition zone diameter.
Materials and methods: In this in-vitro experimental study, suspensions of standard strains of S. mutans (PTCC5027) and Lactobacillus (PTCC1608) were inoculated on Müller-Hinton agar using a sterile swab. 10 g of crushed and dried plants was dissolved in 100 ml of ethanol, and an ethanolic extract was obtained after passing through a filter and evaporation. 10 μl of each extract was poured onto blank discs which were placed on plates containing bacteria. A disc containing the control groups, including 0.2% chlorhexidine and a blank disc, was also placed on the plates. The plates were placed in a jar for 24 hours at 37°C and then the inhibition zone diameter around each disc was measured. Ten replicates were performed for each herbal extract. Data were analyzed by analysis of variance (ANOVA) and post hoc tests.
Results: All four ethanolic herbal extracts were able to inhibit the growth of S. mutans and Lactobacilli. For both bacteria, the largest inhibition zone was observed with chlorhexidine, followed by clove, thyme, garlic, and cinnamon, respectively. There was a significant difference between the inhibition zone diameters formed by the extracts (P<0.01).
Conclusion: Ethanolic extract of clove showed more prominent antibacterial effects than ethanolic extracts of thyme, garlic, and cinnamon.

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