Volume 4, Issue 4 (10-2019)
J Res Dent Maxillofac Sci 2019, 4(4): 17-22 |
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1- Assistant professor, Oral Medecine Dept, Faculty of Dentistry,Tehran Medical Sciences
2- Microbiology Department Medicin Factuly-shahid beheshti University of Medical Sciences
3- Assistant professor, Oral Medecine Dept, Member ship of Dental Material Research Center, Faculty of Dentistry,Tehran medical sciences, Islamic Azad University, Tehran, Iran , nahid_mz_g@yahoo.com
4- Dentist
2- Microbiology Department Medicin Factuly-shahid beheshti University of Medical Sciences
3- Assistant professor, Oral Medecine Dept, Member ship of Dental Material Research Center, Faculty of Dentistry,Tehran medical sciences, Islamic Azad University, Tehran, Iran , nahid_mz_g@yahoo.com
4- Dentist
Abstract: (2871 Views)
Background and Aim: Oral hygiene is important against the development of chronic periodontitis. There are concerns about bacterial resistance to antibiotics. The current study aimed to determine the antimicrobial activity of aqueous garlic extract (Allium sativum) against Porphyromonas gingivalis (P. gingivalis).
Materials and Methods: Aqueous garlic extract was prepared, and the inhibitory effect of the extract was tested against P. gingivalis. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) against the control group (0.2% chlorhexidine) were also determined.
Results: Significant differences were observed concerning the MIC (1.21±0.37 µl) and MBC (1.44±0.67 µl) against P. gingivalis between the aqueous garlic extract and control groups (0.29±0.1 µl; P<0.001). There was a significant difference in the inhibitory zone against P. gingivalis between the aqueous garlic extract group (20.1±1.4 mm) and the control group (27.3±1.8 mm); the inhibitory zone was larger in the control group (P<0.000).
Conclusion: The results suggested that although chlorhexidine exhibited better antimicrobial activity against P. gingivalis, the aqueous garlic extract also showed acceptable results. Further research using different extraction methods and concentrations is suggested.
Materials and Methods: Aqueous garlic extract was prepared, and the inhibitory effect of the extract was tested against P. gingivalis. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) against the control group (0.2% chlorhexidine) were also determined.
Results: Significant differences were observed concerning the MIC (1.21±0.37 µl) and MBC (1.44±0.67 µl) against P. gingivalis between the aqueous garlic extract and control groups (0.29±0.1 µl; P<0.001). There was a significant difference in the inhibitory zone against P. gingivalis between the aqueous garlic extract group (20.1±1.4 mm) and the control group (27.3±1.8 mm); the inhibitory zone was larger in the control group (P<0.000).
Conclusion: The results suggested that although chlorhexidine exhibited better antimicrobial activity against P. gingivalis, the aqueous garlic extract also showed acceptable results. Further research using different extraction methods and concentrations is suggested.
Type of Study: Original article |
Subject:
Oral pathology
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