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:: Volume 5, Issue 1 (Journal of Research in Dental & Maxillofacial Sciences Winter 2020) ::
J Res Dentomaxillofac Sci 2020, 5(1): 40-45 Back to browse issues page
Salivary Flow Rate and pH in Asthmatic and Non-Asthmatic Patients
M Baghban1, S Lesan * 2, T Farrokhnia3, A Kiani4
1- Dentist
2- Assistant professor, Oral Medicine Dept, faculty of Dentistry,Tehran medical sciences, Islamic Azad University, Tehran, Iran , siminlesan@yahoo.com
3- Assistant professor, Oral Medicine Dept, faculty of Dentistry,Tehran medical sciences, Islamic Azad University, Tehran, Iran
4- Associate professor, shahid beheshti university of medical science, Tehran, Iran.
Abstract:   (406 Views)

Background and Aim: Saliva is an essential fluid for protecting the mouth, and any change in its quality or quantity affects the health of the oral cavity. Asthma and the medications used to treat it may decrease salivary flow and change salivary components, including changes in the pH of the dental plaque. The purpose of this study was to determine the salivary flow and pH in asthmatic and non-asthmatic patients referring to the Asthma Clinic of Masih Daneshvari Hospital in Tehran, Iran, in 2019.
Materials and Methods: This cross-sectional study was performed on 70 patients aged 18-60 years (35 asthmatic patients and 35 healthy controls). After completing the datasheets, saliva was collected by the spitting method for 5 minutes. Its flow rate was recorded in ml/minute, and its pH was measured by a pH meter. The results were analyzed via SPSS 20 software according to the t-test and Mann-U-Whitney statistical test.
Results: The mean salivary flow rate was 4.22 ml/minute in the asthmatic group and 5.44 ml/minute in the healthy group (P<0.005). The mean salivary pH in the asthmatic patients and the control group was 6.9 and 7.1 (P<0.005), respectively, indicating that salivary flow rate and pH were significantly lower compared to the healthy group. Statistical analyses also showed that the higher the frequency of drug use, the greater the decrease in the salivary flow (P<0.005).
Conclusion: It seems that asthma and the drugs used for its treatment reduce salivary flow and pH. 

Keywords: Asthma, Anti-Asthmatic Agents, Saliva, Case-Control Studies
Full-Text [PDF 233 kb]   (144 Downloads) |   |   Full-Text (HTML)  (293 Views)  
Type of Study: Original article | Subject: Oral medicine
* Corresponding Author Address: Islamic Azad University, Tehran, Iran
References
1. Bulthuis MS, Jan Jager DH, Brand HS. Relationship among perceived stress, xerostomia, and salivary flow rate in patients visiting a saliva clinic. Clin Oral Investig. 2018 Dec;22(9):3121-7.
2. Lenander-Lumikari M, Laurikainen K, Kuusisto P, Vilja P. Stimulated salivary flow rate and composition in asthmatic and non-asthmatic adults. Arch Oral Biol. 1998 Feb;43(2):151-6.
3. Alaki S, Ashiry E, Bakry N, Baghlaf K. The effects of asthma and asthma medication on dental caries and salivary characteristics in children. Oral Health Prev Dent. 2013;11(2):113-20.
4. Santos NC, Jamelli S, Costa L, Baracho Filho C, Medeiros D, Rizzo JA, et al. Assessing caries, dental plaque and salivary flow in asthmatic adolescents using inhaled corticosteroids. Allergol Immunopathol (Madr). 2012 Jul-Aug;40(4):220-4.
5. Stensson M, Wendt LK, Koch G, Oldaeus G, Lingström P, Birkhed D. Caries prevalence, caries-related factors and plaque pH in adolescents with long-term asthma. Caries Res. 2010;44(6):540-6.
6. Sag C, Ozden FO, Acikgoz G, Anlar FY. The effects of combination treatment with a long-acting beta2-agonist and a corticosteroid on salivary flow rate, secretory immunoglobulin A, and oral health in children and adolescents with moderate asthma: a 1-month, single-blind clinical study. Clin Ther. 2007 Oct;29(10):2236-42.
7. Shashikiran ND, Reddy VV, Raju PK. Effect of antiasthmatic medication on dental disease: dental caries and periodontal disease. J Indian Soc Pedod Prev Dent. 2007 Apr-Jun;25(2):65-8.
8. Laurikainen K, Kuusisto P. Comparison of the oral health status and salivary flow rate of asthmatic patients with those of nonasthmatic adults--results of a pilot study. Allergy. 1998 Mar 1;53(3):316-9.
9. Thomas MS, Parolia A, Kundabala M, Vikram M. Asthma and oral health: a review. Aust Dent J. 2010 Jun;55(2):128-33.
10. Rezende G, Dos Santos NML, Stein C1, Hilgert JB, Faustino-Silva DD. Asthma and oral changes in children: Associated factors in a community of southern Brazil. Int J Paediatr Dent. 2019 Jul;29(4):456-63.
11. Ryberg M, Möller C, Ericson T. Saliva composition in asthmatic patients after treatment with two dose levels of a beta 2-adrenoceptor agonist. Arch Oral Biol. 1990;35(12):945-8.
12. Shannon IL, Suddick RP, Dowd FJ Jr. Saliva: composition and secretion. Monogr Oral Sci. 1974 Jun;2:1-103.
13. Heft MW, Baum BJ. Unstimulated and stimulated parotid salivary flow rate in individuals of different ages. J Dent Res. 1984 Oct;63(10):1182-5.
14. Steinsvåg SK, Skadberg B, Bredesen K. Nasal symptoms and signs in children suffering from asthma. Int J Pediatr Otorhi. 2007 Apr 1;71(4):615-21.
15. Hyyppä T, Paunio K. Oral health and salivary factors in children with asthma. Proc Finn Dent Soc. 1979;75(1-2):7-10.
16. Ersin NK, Guelen F, Eronat N, Cogulu D, Demir E, Tanac R, et al. Oral and dental manifestations of young asthmatics related to medication, severity and duration of condition. Pediatr Int. 2006 Dec;48(6):549-54.
17. Cao CF, Smith QT. Crevicular fluid myeloperoxidase at healthy, gingivitis and periodontitis sites. J Clin Periodontol. 1989 Jan;16(1):17-20.
18. Watanabe M, Sano H, Tomita K, Yamasaki A, Kurai J, Hasegawa Y, et al. A nocturnal decline of salivary pH associated with airway hyperresponsiveness in asthma. J Med Invest. 2010 Aug;57(3-4):260-9.
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Baghban M, Lesan S, Farrokhnia T, Kiani A. Salivary Flow Rate and pH in Asthmatic and Non-Asthmatic Patients. J Res Dentomaxillofac Sci. 2020; 5 (1) :40-45
URL: http://jrdms.dentaliau.ac.ir/article-1-268-en.html


Volume 5, Issue 1 (Journal of Research in Dental & Maxillofacial Sciences Winter 2020) Back to browse issues page
Journal of Research in Dental and Maxillofacial Sciences
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